Quality-of-life issues and symptoms reported by patients living with haematological malignancy: a qualitative study.

Autor:	Goswami P; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK., Oliva EN; Haematology Unit, Grande Ospedale Metropolitano, Reggio Calabria, Italy., Ionova T; St Petersburg State University Medical Center and Multinational Centre for Quality of Life Research, St Petersburg, Russia., Else R; Patient Research Partner, Milton Keynes, UK., Kell J; Cardiff and Vale University Health Board, Cardiff, UK., Fielding AK; University College London Cancer Institute, London, UK., Jennings DM; Royal Surrey County Hospital NHS Foundation Trust, Guildford, Surrey, UK., Karakantza M; Leeds Teaching Hospitals NHS Trust, Leeds, UK., Al-Ismail S; Singleton Hospital, ABM University Health Board, Swansea, UK., Collins GP; Oxford University Hospitals NHS Trust, Oxford, UK., McConnell S; Leeds Teaching Hospitals NHS Trust, Leeds, UK., Langton C; Leeds Teaching Hospitals NHS Trust, Leeds, UK., Salek S; School of Life and Medical Science, University of Hertfordshire, Health Research Building (2F412), College Lane, Hatfield, Herts AL10 9BR, UK.
Jazyk:	angličtina
Zdroj:	Therapeutic advances in hematology [Ther Adv Hematol] 2020 Oct 07; Vol. 11, pp. 2040620720955002. Date of Electronic Publication: 2020 Oct 07 (Print Publication: 2020).
DOI:	10.1177/2040620720955002
Abstrakt:	Background: Our aim was to identify health-related quality-of-life (HRQoL) issues and symptoms in patients with haematological malignancies (HMs) and develop a conceptual framework to reflect the inter-relation between them. Methods: A total of 129 patients with HMs were interviewed in a UK multicentre qualitative study. All interviews were audio recorded, transcribed and analysed using NVivo-11. Results: Overall, 34 issues were reported by patients and were grouped into two parts: quality of life (QoL) and symptoms. The most prevalent HRQoL issues were: eating and drinking habits; social life; physical activity; sleep; and psychological well-being. Furthermore, most prevalent disease-related symptoms were: tiredness; feeling unwell; breathlessness; lack of energy; and back pain. The most prevalent treatment side effects were: tiredness; feeling sick; disturbance in sense of taste; and breathlessness. Conclusions: Both HMs and their treatments have a significant impact on patients' HRQoL, in particular on issues such as job-role change, body image and impact on finances. Competing Interests: Conflict of interest statement: The authors declare that there is no conflict of interest. (© The Author(s), 2020.)
Databáze:	MEDLINE
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