[Redo surgery in children with epilepsy].

Autor:	Khachatryan VA; Almazov National Medical Research Center, St. Petersburg, Russia., Mamatkhanov MR; Almazov National Medical Research Center, St. Petersburg, Russia., Larionov SN; Almazov National Medical Research Center, St. Petersburg, Russia., Lebedev KE; Almazov National Medical Research Center, St. Petersburg, Russia.
Jazyk:	ruština
Zdroj:	Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko [Zh Vopr Neirokhir Im N N Burdenko] 2020; Vol. 84 (5), pp. 21-27.
DOI:	10.17116/neiro20208405121
Abstrakt:	Objective: To analyze the causes of ineffective operations and the results of redo surgery in children with recurrent epileptic seizures. Material and Methods: The results of redo surgery were analyzed in 41 (10.6%) out of 387 children with drug resistant epilepsy treated surgically at the Russian Polenov Neurosurgical Institute for the period from 1994 to 2014. Patients with recurrent epilepsy after temporal resection ( n =20), extratemporal resection ( n =7), multifocal resection ( n =6), callosotomy and stereotaxic destruction ( n =8) were selected for analysis. Results: Seizure-free period ranged from early postoperative period to 4 years. According to MRI data, lesions were not completely resected during primary surgery in 23 (56.1%) children. The causes of inefficiency of primary operations were inaccurate identification of epileptic focus in 15 (36.6%) patients; incomplete resection of epileptogenic and / or epileptic foci or incomplete disconnection of paroxysmal activity distribution pathways in 14 (34.1%) cases; epileptic foci de novo in 8 (19.5%) cases; inadequate surgical strategy in 4 (9.8%) patients. Redo surgery usually implied an extended previous resection in 34 (82.9%) patients. Engel I outcome after 3 years was achieved in 41.1% of patients, after 5 years - 38.3%, after 10 years - 36.4%. Conclusion: Redo surgery is quite effective and minimally traumatic. Therefore, patients with recurrent epileptic seizures should be considered as candidates for repeated operations if previous interventions turned out to be ineffective.
Databáze:	MEDLINE
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