The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study.

Autor: Kang W; Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, 101149, China., Du J; Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, 101149, China., Yang S; Chongqing Public Health Medical Center, No.109, Baoyu Road, Geleshan Town, Shapingba District, Chongqing, 400036, China., Yu J; Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, 101149, China., Chen H; Shenyang Chest Hospital, No. 11 Beihai Street, Dadong District, Shenyang, 110044, China., Liu J; Guang Zhou Chest Hospital, No.62, Heng Zhi Gang Road, Yuexiu District, Guangzhou, 510095, Guangdong, China., Ma J; Chest Hospital of Xinjiang, No.106, Yan 'An Road, Tianshan District, Urumqi, 830049, Xinjiang, China., Li M; The Third People's Hospital of Kunming, No. 319 Wu Jing Road, Kunming City, 650041, Yunnan Province, China., Qin J; Shandong Provincial Chest Hospital, No. 12, Lieshishandong Road, Licheng District, Jinan, 250000, Shandong, China., Shu W; Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, 101149, China., Zong P; Jiangxi Chest (Third People) Hospital, No.346 Dieshan Road, Donghu District, Nanchang City, 330006, Jiangxi Province, China., Zhang Y; Chang Chun Infectious Diseases Hospital, No. 2699, Sandao Section, Changji South Line, Erdao District, Changchun City, 130123, Jilin Province, China., Dong Y; Taiyuan Fourth People's Hospital, Number 231, Xikuang Street, Wan Bailin District, Taiyuan City, 030024, Shanxi Province, China., Yang Z; Fuzhou Pulmonary Hospital of Fujian, No. 2, Lakeside, Cangshan District, Fuzhou, 350008, China., Mei Z; Tianjin Haihe Hospital, Number 890, Shuanggangzhenjingu Road, Jinnan District, Tianjin City, 300350, China., Deng Q; Third People's Hospital of Shenzhen, 29 Bulan Road, District Longgang, Shenzhen, 518112, China., Wang P; The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, China., Han W; Weifang NO.2 People's Hospital, No. 7th Yuanxiao Street Kuiwen District, Weifang, 261041, China., Wu M; The Fifth People's Hospital of Suzhou, No. 10, Guangqian Road, Suzhou City, 215000, Jiangsu Province, China., Chen L; Affiliated Hospital of Zunyi Medical College, No. 149 Delian Road, Zunyi, 563000, Guizhou, China., Zhao X; The Fifth People's Hospital of Wuxi, No. 1215, GuangRui Road, Wuxi, 214001, China., Tan L; TB Hospital of Siping City, No. 10 Dongshan Road, Tiedong District, Siping City, 136001, Jilin Province, China., Li F; Baoding Hospital for Infectious Disease, No. 608 Dongfeng East Road, Lianchi District, Baoding City, 071000, Hebei Province, China., Zheng C; The First Affiliated Of XiaMen University, ZhenhaiRoud, Siming District, Xiamen City, Fujian Province, China., Liu H; Shenyang Chest Hospital, No. 11 Beihai Street, Dadong District, Shenyang, 110044, China., Li X; Guang Zhou Chest Hospital, No.62, Heng Zhi Gang Road, Yuexiu District, Guangzhou, 510095, Guangdong, China., Ertai A; Chest Hospital of Xinjiang, No.106, Yan 'An Road, Tianshan District, Urumqi, 830049, Xinjiang, China., Du Y; The Third People's Hospital of Kunming, No. 319 Wu Jing Road, Kunming City, 650041, Yunnan Province, China., Liu F; Shandong Provincial Chest Hospital, No. 12, Lieshishandong Road, Licheng District, Jinan, 250000, Shandong, China., Cui W; Chang Chun Infectious Diseases Hospital, No. 2699, Sandao Section, Changji South Line, Erdao District, Changchun City, 130123, Jilin Province, China., Wang Q; Taiyuan Fourth People's Hospital, Number 231, Xikuang Street, Wan Bailin District, Taiyuan City, 030024, Shanxi Province, China., Chen X; Fuzhou Pulmonary Hospital of Fujian, No. 2, Lakeside, Cangshan District, Fuzhou, 350008, China., Han J; Tianjin Haihe Hospital, Number 890, Shuanggangzhenjingu Road, Jinnan District, Tianjin City, 300350, China., Xie Q; Third People's Hospital of Shenzhen, 29 Bulan Road, District Longgang, Shenzhen, 518112, China., Feng Y; The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, China., Liu W; Weifang NO.2 People's Hospital, No. 7th Yuanxiao Street Kuiwen District, Weifang, 261041, China., Tang P; The Fifth People's Hospital of Suzhou, No. 10, Guangqian Road, Suzhou City, 215000, Jiangsu Province, China., Zhang J; Affiliated Hospital of Zunyi Medical College, No. 149 Delian Road, Zunyi, 563000, Guizhou, China., Zheng J; The Fifth People's Hospital of Wuxi, No. 1215, GuangRui Road, Wuxi, 214001, China., Chen D; Baoding Hospital for Infectious Disease, No. 608 Dongfeng East Road, Lianchi District, Baoding City, 071000, Hebei Province, China., Yao X; The First Affiliated Of XiaMen University, ZhenhaiRoud, Siming District, Xiamen City, Fujian Province, China., Ren T; Shenyang Chest Hospital, No. 11 Beihai Street, Dadong District, Shenyang, 110044, China., Li Y; Guang Zhou Chest Hospital, No.62, Heng Zhi Gang Road, Yuexiu District, Guangzhou, 510095, Guangdong, China., Li Y; Chest Hospital of Xinjiang, No.106, Yan 'An Road, Tianshan District, Urumqi, 830049, Xinjiang, China., Wu L; The Third People's Hospital of Kunming, No. 319 Wu Jing Road, Kunming City, 650041, Yunnan Province, China., Song Q; Shandong Provincial Chest Hospital, No. 12, Lieshishandong Road, Licheng District, Jinan, 250000, Shandong, China., Yang M; Chongqing Public Health Medical Center, No.109, Baoyu Road, Geleshan Town, Shapingba District, Chongqing, 400036, China., Zhang J; Chang Chun Infectious Diseases Hospital, No. 2699, Sandao Section, Changji South Line, Erdao District, Changchun City, 130123, Jilin Province, China., Liu Y; Tianjin Haihe Hospital, Number 890, Shuanggangzhenjingu Road, Jinnan District, Tianjin City, 300350, China., Guo S; The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, China., Yan K; Weifang NO.2 People's Hospital, No. 7th Yuanxiao Street Kuiwen District, Weifang, 261041, China., Shen X; The Fifth People's Hospital of Suzhou, No. 10, Guangqian Road, Suzhou City, 215000, Jiangsu Province, China., Lei D; Affiliated Hospital of Zunyi Medical College, No. 149 Delian Road, Zunyi, 563000, Guizhou, China., Zhang Y; Baoding Hospital for Infectious Disease, No. 608 Dongfeng East Road, Lianchi District, Baoding City, 071000, Hebei Province, China., Yan X; Chongqing Public Health Medical Center, No.109, Baoyu Road, Geleshan Town, Shapingba District, Chongqing, 400036, China. 2429918342@qq.com., Li L; Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, 101149, China. liliang@tb123.org., Tang S; Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, 101149, China. tangsj1106@hotmail.com.
Jazyk: angličtina
Zdroj: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 2021 Apr; Vol. 40 (4), pp. 787-800. Date of Electronic Publication: 2020 Oct 22.
DOI: 10.1007/s10096-020-04077-2
Abstrakt: In clinical practice, PTB patients have concurrent many types of comorbidities such as pneumonia, liver disorder, diabetes mellitus, hematological disorder, and malnutrition. Detecting and treating specific comorbidities and preventing their development are important for PTB patients. However, the prevalence of most comorbid conditions in patients with PTB is not well described. We conducted a large-scale, multicenter, observational study to elucidate and illustrate the prevalence rates of major comorbidities in inpatients at 21 hospitals in China. The 19 specific comorbidities were selected for analysis in this patient cohort, and stratified the inpatient cohort according to age and gender. A total of 355,929 PTB inpatients were included, with a male:female ratio of 1.98 and the proportion of ≥ 65 years PTB inpatients was the most. Approximately 70% of PTB inpatients had at least one defined type of comorbidity. The prevalence of 19 specific comorbidities in inpatients with PTB was analyzed, with pneumonia being the most common comorbidity. The prevalence of most comorbidities was higher in males with PTB except thyroid disorders, mental health disorders, etc. The prevalence of defined most comorbidities in patients with PTB tended to increase with increasing age, although some specific comorbidities tended to increase initially then decrease with increasing age. Our study describes multiple clinically important comorbidities among PTB inpatients, and their prevalence between different gender and age groups. The results will enhance the clinical aptitude of physicians who treat patients with PTB to recognize, diagnose, and treat PTB comorbidities early.
Databáze: MEDLINE
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