In Utero Vertical Transmission of Coronavirus Disease 2019 in a Severely Ill 29-week Preterm Infant.

Autor:	Gupta A; Division of Neonatology, Department of Pediatrics, NYCH + H/Metropolitan Hospital Center, New York City, New York., Malhotra Y; Division of Neonatology, Lewis M Fraad Department of Pediatrics, NYCH + H/Jacobi Medical Center, New York City, New York., Patil U; Division of Neonatology, Department of Pediatrics, NYCH + H/Elmhurst Hospital Center, New York City, New York., Muradas AR; Division of Neonatology, Department of Pediatrics, NYCH + H/Metropolitan Hospital Center, New York City, New York., Lee WT; Diagnostic Immunology Laboratory Wadsworth Center, New York State Department of Health David Axelrod Institute for Public Health, Albany, New York., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York., Amanat F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York., Clare CA; Department of Obstetrics and Gynecology, New York Medical College, NYCH + H/Metropolitan Hospital Center, New York City, New York., Vinod S; Division of Neonatology, Department of Pediatrics, NYCH + H/Metropolitan Hospital Center, New York City, New York., Ghaly E; Division of Neonatology, Department of Pediatrics, NYCH + H/Metropolitan Hospital Center, New York City, New York.
Jazyk:	angličtina
Zdroj:	AJP reports [AJP Rep] 2020 Jul; Vol. 10 (3), pp. e270-e274. Date of Electronic Publication: 2020 Sep 16.
DOI:	10.1055/s-0040-1715177
Abstrakt:	Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) or coronavirus disease 2019 (COVID-19) is currently in worldwide pandemic state with very limited data about the mode of transmission to the growing fetus. There are a few published cases of COVID-19 infection in the infants born to COVID-19 positive mothers where most of the reported cases were either mildly symptomatic with positive COVID-19 polymerase chain reaction (PCR) or had negative COVID-19 PCR raising the question of vertical transmission. We present a case of likely intrauterine transmission of COVID-19 infection in a critically ill premature infant born to a COVID-19 infected mother and describing her clinical course thus far. The clinical presentation in the infant is consistent with COVID-19 infection described so far in literature along with positive PCR, and positive COVID-19 serology: immunoglobulin G, immunoglobulin M, and immunoglobulin A. Competing Interests: Conflict of Interest None declared. (The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).)
Databáze:	MEDLINE
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