The Use of Botulinum Neurotoxin Type A in Aesthetics: Key Clinical Postulates.
| Autor: | Nestor MS; Center for Clinical and Cosmetic Research & Center for Cosmetic Enhancement, Aventura, Florida; †Department of Dermatology and Cutaneous Surgery and the Department of Surgery, Division of Plastic Surgery, University of Miami Leonard Miller School of Medicine, Miami, Florida; ‡Larkin Community Hospital, Palm Springs Campus, Hialeah, Florida; §Toxin Science Limited, Wrexham, United Kingdom; ¶Botulinum Research Center, Institute of Advanced Sciences, Dartmouth, Massachusetts; ‖Galderma Aesthetic and Corrective Global Business Unit, Uppsala, Sweden., Kleinfelder RE, Pickett A |
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| Jazyk: | angličtina |
| Zdroj: | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2017 Dec; Vol. 43 Suppl 3, pp. S344-S362. |
| DOI: | 10.1097/DSS.0000000000001412 |
| Abstrakt: | Background: The most common aesthetic procedure performed worldwide is the injection of botulinum neurotoxin Type A (BoNT-A). Aesthetic providers must fully comprehend the objective scientific data, theoretical mechanisms of action, and differences between brands of BoNT-A. Objective: To determine and review the relevant clinical postulates for the use of botulinum toxin in aesthetics. Materials and Methods: The BoNT-A clinical postulates presented here discuss how each brand of BoNT-A acts identically, how the molecular potency may vary between the different products, how patient age, gender, genetics, and muscle mass cause variation in toxin receptor number and density, and how both practitioner and patient can affect toxin distribution. Results: A total of 8 clinical postulates have been identified that are key to understanding the use of botulinum toxin in aesthetics and to obtaining the best clinical results. Conclusion: All of these factors affect the potential efficacy of the injected toxin and hence the aesthetic results obtained. |
| Databáze: | MEDLINE |
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