Efficacy of Surgical Excision and Brachytherapy in the Treatment of Keloids: A Retrospective Cohort Study.
| Autor: | Daurade M; At the Centre Hospitalier Lyon Sud in Pierre-Bénite, Lyon, France, Mathieu Daurade, MD, is a maxillofacial surgery resident; Pierre Breton, MD, PhD, is Head of the Maxillofacial Surgery, Plastic Surgery and Stomatology Department; Nathalie Rouard, MD, is Radiotherapy Physician; Fabrice Lorchel, MD, is Head of the Brachytherapy Department; Badr Ibrahim, MD, is an ear, nose, and throat surgeon; and Nicolas Sigaux, MD, is a maxillofacial surgeon. The authors have disclosed no financial relationships related to this article. Submitted October 20, 2019; accepted in revised form December 10, 2019., Breton P, Rouard N, Lorchel F, Ibrahim B, Sigaux N |
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| Jazyk: | angličtina |
| Zdroj: | Advances in skin & wound care [Adv Skin Wound Care] 2020 Nov; Vol. 33 (11), pp. 1-6. |
| DOI: | 10.1097/01.ASW.0000717228.02752.4e |
| Abstrakt: | Objective: To demonstrate the efficacy of a protocol combining surgical excision and high-dose-rate brachytherapy for treatment of keloids. Methods: The authors performed a unicentric retrospective cohort study between 2013 and 2018. The minimum follow-up was 12 months. All patients treated for keloids at the authors' institution were included. Extralesional excision was performed with placement of a brachytherapy sheath under the skin. The total dose of irradiation was 18 Gy. The postoperative results were evaluated for aesthetic and functional outcomes with a validated scale, as well as the presence or absence of recurrence. Results: Fifteen patients were lost to follow-up. Thirty-eight patients with 67 keloids were included. The control rate was 94%. The aesthetic and functional outcomes were considered good in 62% of cases. The main limitation of the study was the small patient population. Conclusions: Extralesional excision combined with postoperative high-dose-rate brachytherapy seems to be one of the most effective invasive protocols to treat and prevent keloids. |
| Databáze: | MEDLINE |
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