| Autor: |
Zakrzewski W; Department of Experimental Surgery and Biomaterial Research, Wroclaw Medical University, Bujwida 44, 50-345 Wroclaw, Poland., Dobrzynski M; Department of Conservative Dentistry and Pedodontics, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland., Nowicka J; Department of Microbiology, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, Poland., Pajaczkowska M; Department of Microbiology, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, Poland., Szymonowicz M; Department of Experimental Surgery and Biomaterial Research, Wroclaw Medical University, Bujwida 44, 50-345 Wroclaw, Poland., Targonska S; Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland., Sobierajska P; Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland., Wiglusz K; Department of Analytical Chemistry, Wroclaw Medical University, Borowska 211 A, 50-566 Wroclaw, Poland., Dobrzynski W; Student Scientific Circle at the Department of Dental Materials, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Akademicki Sq. 17, 41-902 Bytom, Poland., Lubojanski A; Department of Experimental Surgery and Biomaterial Research, Wroclaw Medical University, Bujwida 44, 50-345 Wroclaw, Poland., Fedorowicz S; Department of Microbiology, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, Poland., Rybak Z; Department of Experimental Surgery and Biomaterial Research, Wroclaw Medical University, Bujwida 44, 50-345 Wroclaw, Poland., Wiglusz RJ; Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland. |
| Abstrakt: |
The research has been carried out with a focus on the assessment of the antimicrobial efficacy of pure nanohydroxyapatite, Cu 2+ -doped nanohydroxyapatite, ozonated olive oil-loaded nanohydroxyapatite, and Cu 2+ -doped nanohydroxyapatite, respectively. Their potential antimicrobial activity was investigated against Streptococcus mutans, Lactobacillus rhamnosus , and Candida albicans . Among all tested materials, the highest efficacy was observed in terms of ozonated olive oil. The studies were performed using an Ultraviolet-Visible spectrophotometry (UV-Vis), electron microscopy, and statistical methods, by determining the value of Colony-Forming Units (CFU/mL) and Minimal Inhibitory Concentration (MIC). |
