| Autor: |
Ushkalova EA; Peoples' Friendship University of Russia (RUDN University), Moscow, Russia., Zyryanov SK; Peoples' Friendship University of Russia (RUDN University), Moscow, Russia., Zatolochina KE; Peoples' Friendship University of Russia (RUDN University), Moscow, Russia. |
| Jazyk: |
ruština |
| Zdroj: |
Khirurgiia [Khirurgiia (Mosk)] 2020 (10), pp. 104-111. |
| DOI: |
10.17116/hirurgia2020101104 |
| Abstrakt: |
The article discusses the place of symptomatic slow-acting drugs in current guidelines for the treatment of osteoarthritis. Special emphasis is put ot glucosamine preparations, the attitude towards which, until recently, was ambiguous. The results of experimental and clinical studies demonstrating the advantages of crystalline glucosamine sulfate over preparations/food additives of glucosamine hydrochloride are presented. The differences in the pharmacodynamics and pharmacokinetics of glucosamine sulfate and glucosamine hydrochloride, which may be the reason for the ineffectiveness of the latter in clinical trials, are discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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