A clinical trial of volume- versus pressure-controlled intraoperative ventilation during laparoscopic bariatric surgeries.

Autor: Ghodraty MR; Department of Anesthesiology, Iran University of Medical Sciences, Tehran, Iran., Pournajafian AR; Department of Anesthesiology, Iran University of Medical Sciences, Tehran, Iran., Tavoosian SD; Department of Anesthesiology, Iran University of Medical Sciences, Tehran, Iran., Khatibi A; Department of Anesthesiology, Iran University of Medical Sciences, Tehran, Iran., Safari S; Department of Surgery, Iran University of Medical Sciences, Tehran, Iran., Motlagh SD; Department of Anesthesiology, Iran University of Medical Sciences, Tehran, Iran., Abhari MB; Department of Community Medicine, Iran University of Medical Sciences, Tehran, Iran., Shafighnia S; Department of Anesthesiology, Iran University of Medical Sciences, Tehran, Iran., Porhomayon J; Department of Anesthesiology, University at Buffalo, Buffalo, New York, United States., Nader ND; Department of Anesthesiology, University at Buffalo, Buffalo, New York, United States. Electronic address: nnader@buffalo.edu.
Jazyk: angličtina
Zdroj: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery [Surg Obes Relat Dis] 2021 Jan; Vol. 17 (1), pp. 81-89. Date of Electronic Publication: 2020 Sep 02.
DOI: 10.1016/j.soard.2020.08.034
Abstrakt: Background: Intra-operative ventilation is often challenging in patients with morbid obesity undergoing bariatric surgery.
Objectives: To test the noninferiority of pressure-controlled ventilation (PCV) to volume-controlled ventilation (VCV) in respiratory mechanics.
Setting: Bariatric Surgery Center, Iran.
Methods: In a randomized open-labeled clinical trial, 66 individuals with morbid obesity undergoing laparoscopic bariatric surgeries underwent intraoperative ventilation with either PCV or VCV. The measurements taken were peak and mean airway pressures (H 2 O), partial pressure of arterial oxygen (PaO 2 ), partial pressure of arterial carbon dioxide (PaCO 2 ) and end-tidal carbon dioxide (CO 2 ). We additionally collected pulse-oximetric oxygen saturation, inspiratory concentration of oxygen (FiO 2 ), and hemodynamic variables. Data were analyzed with repeated measures over the time of intubation, after peritoneal insufflation, and every 15 minutes, thereafter up to one hour.
Results: PCV mode was successful to sustain adequate ventilation in 97% of the patients, which was similar to the 94% success rate of the VCV mode. Peak airway pressure increased 6 cmH 2 O and end-tidal CO 2 rose by 5 mm Hg after abdominal insufflation in both groups (P = .850 and .376). Alveolar-arterial oxygen gradient similarly increased within 30 minutes after tracheal intubation both in PCV and VCV groups, with small trend of being higher in the VCV group. The ratio of dead space to tidal volumes (VD/VT) did not have a meaningful change (P = .724).
Conclusion: PCV was noninferior to VCV during laparoscopic bariatric surgery. Either mode of ventilation could be alternatively used during the anesthesia care of these patients.
(Copyright © 2020 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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