Laryngoscopy Grade Improvement and Difficult Airway Resolution in Infants With Robin Sequence Undergoing Mandibular Distraction Osteogenesis: A Multi-Institutional Study.

Autor:	Siegel N; Department of Plastic and Reconstructive Surgery, 1500The Johns Hopkins Hospital, Baltimore, MD, USA., Lopez J; Department of Plastic and Reconstructive Surgery, 1500The Johns Hopkins Hospital, Baltimore, MD, USA., Shi AC; Department of Plastic and Reconstructive Surgery, 1500The Johns Hopkins Hospital, Baltimore, MD, USA., Neimanis S; Division of Plastic and Reconstructive Surgery, Department of Surgery, 6923University of Rochester Medical Center, Rochester, NY, USA., Jodeh D; Department of Plastic and Reconstructive Surgery, 7582Johns Hopkins All Children's Hospital, St. Petersburg, FL, USA., Khavanin N; Department of Plastic and Reconstructive Surgery, 1500The Johns Hopkins Hospital, Baltimore, MD, USA., Redett RJ; Department of Plastic and Reconstructive Surgery, 1500The Johns Hopkins Hospital, Baltimore, MD, USA., Sterni LM; Division of Pulmonology, Department of Pediatrics, 1500The Johns Hopkins Hospital, Baltimore, MD, USA., Walsh JM; Department of Otolaryngology-Head and Neck Surgery, 1500The Johns Hopkins Hospital, Baltimore, MD, USA., Dalesio NM; Department of Anesthesiology, 1500The Johns Hopkins Hospital, Baltimore, MD, USA., Rottgers SA; Department of Plastic and Reconstructive Surgery, 7582Johns Hopkins All Children's Hospital, St. Petersburg, FL, USA., Morrison CS; Division of Plastic and Reconstructive Surgery, Department of Surgery, 6923University of Rochester Medical Center, Rochester, NY, USA., Steinberg JP; Department of Plastic and Reconstructive Surgery, 1500The Johns Hopkins Hospital, Baltimore, MD, USA.
Jazyk:	angličtina
Zdroj:	The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association [Cleft Palate Craniofac J] 2021 Jul; Vol. 58 (7), pp. 805-814. Date of Electronic Publication: 2020 Oct 08.
DOI:	10.1177/1055665620964052
Abstrakt:	Objective: Mandibular distraction osteogenesis (MDO) aims to relieve tongue-based airway obstruction in Robin Sequence (RS). We investigated direct laryngoscopy grade (DLG) improvement and difficult airway (DA) resolution following MDO. Design: Retrospective cohort analysis. Setting: Three tertiary care institutions. Patients: Sixty-four infants with RS who underwent a single MDO procedure in their first year of life were identified from January 2010 to January 2019. Main Outcome Measures: The primary outcome was DLG pre- and post-MDO. Secondary outcomes included DA designation, pre- and post-MDO polysomnographic assessment for obstructive sleep apnea (OSA), length of stay, need for gastrostomy, and major/minor adverse events. Results: Median DLG improved from II pre-MDO to I at the time of distractor removal (n = 43, P < .001). No significant change was seen in patients with a third recorded time point (eg, palatoplasty; n = 78, P = .52). Twenty-six (47%) of 55 patients were designated as DA pre-MDO, and 10 (18%) of 55 patients retained the label post-MDO ( P < .01). Five (50%) of these 10 patients appeared to be inappropriately retained. Median obstructive apnea-hypopnea index improved from 38.6 (range 31.2-62.8) pre-MDO to 2.9 (range 1-3.9) post-MDO (n = 12; P = .002). Conclusion: Mandibular distraction osteogenesis allowed for DLG improvement that was stably maintained as well as functional improvement in OSA, with minimal morbidity. Difficult airway designation persisted in the electronic record of some infants despite clinical resolution.
Databáze:	MEDLINE
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