Two cases with postural axial tremor: Consider a genetic origin.

Autor: Zutt R; Department of Neurology, Haga Teaching Hospital, the Hague, the Netherlands. Electronic address: r.zutt@hagaziekenhuis.nl., Elting JW; Univ Groningen, Univ Med Ctr Groningen, Dept Neurol, 9713, Groningen, NL, the Netherlands; Expertise Center Movement Disorders Groningen, University Medical Center Groningen (UMCG), Groningen, the Netherlands., Santens P; Department of Neurology, Ghent University Hospital, Ghent, Belgium., Luijckx GJR; Univ Groningen, Univ Med Ctr Groningen, Dept Neurol, 9713, Groningen, NL, the Netherlands., Tijssen MAJ; Univ Groningen, Univ Med Ctr Groningen, Dept Neurol, 9713, Groningen, NL, the Netherlands; Expertise Center Movement Disorders Groningen, University Medical Center Groningen (UMCG), Groningen, the Netherlands. Electronic address: m.a.j.de.koning-tijssen@umcg.nl.
Jazyk: angličtina
Zdroj: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2020 Aug; Vol. 77, pp. 152-154.
DOI: 10.1016/j.parkreldis.2020.04.013
Abstrakt: We present two cases with postural axial tremor predominantly involving the head, trunk, and shoulders. In the first patient, the postural tremor occurred in multiple attacks a day lasting approximately 10 min. The second patient developed a progressive tremor of his head and arms, worsened during sitting and standing. Electrophysiological supported the postural axial tremor in both patients with a varying 3-10 Hz tremor frequency between different muscles and within the same muscles at different times. Postural axial tremor is a rare and complex movement disorder. The majority of cases are caused by acquired cerebellar pathology. However, isolated cases with underlying genetic disorders are described in literature. Here, we illustrate how to differentiate paroxysmal axial tremor from other axial hyperkinetic movement disorders and extend the genetic heterogeneity of this intriguing movement disorder phenotype.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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