SARS-COV-2 infection during pregnancy, a risk factor for eclampsia or neurological manifestations of COVID-19? Case report.

Autor: Garcia Rodriguez A; Department of Anaesthesiology and Critical Care, University Complex Hospital of Leon, 24071, City Leon, Spain., Marcos Contreras S; Department of Anaesthesiology and Critical Care, University Complex Hospital of Leon, 24071, City Leon, Spain. s.marcos89@gmail.com., Fernandez Manovel SM; Department of Anaesthesiology and Critical Care, University Complex Hospital of Leon, 24071, City Leon, Spain., Marcos Vidal JM; Department of Anaesthesiology and Critical Care, University Complex Hospital of Leon, 24071, City Leon, Spain., Diez Buron F; Department of Anaesthesiology and Critical Care, University Complex Hospital of Leon, 24071, City Leon, Spain., Fernandez Fernandez C; Department of Obstetrics and Gynaecology, University Complex Hospital of Leon, 24071, City Leon, Spain., Riveira Gonzalez MDC; Department of Neurology, University Complex Hospital of Leon, 24071, City Leon, Spain.
Jazyk: angličtina
Zdroj: BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2020 Oct 06; Vol. 20 (1), pp. 587. Date of Electronic Publication: 2020 Oct 06.
DOI: 10.1186/s12884-020-03275-2
Abstrakt: Background: There are no published cases of tonic-clonic seizures and posterior bilateral blindness during pregnancy and Severe Acute Respiratory Syndrome (SARS) Coronavirus (COV) 2 (SARS-COV-2) infection. We do not just face new and unknown manifestations, but also how different patient groups are affected by SARS-COV-2 infection, such as pregnant women. Coronavirus Disease 2019 (COVID-19), preeclampsia, eclampsia and posterior reversible leukoencephalopathy share endothelium damage and similar pathophysiology.
Case Presentation: A 35-year-old pregnant woman was admitted for tonic-clonic seizures and SARS-COV-2 infection. She had a normal pregnancy control and no other symptoms before tonic-clonic seizures development. After a Caesarean section (C-section) she developed high blood pressure, and we initiated antihypertensive treatment with labetalol, amlodipine and captopril. Few hours later she developed symptoms of cortical blindness that resolved in 72 h with normal brain computed tomography (CT) angiography.
Conclusion: The authors conclude that SARS COV-2 infection could promote brain endothelial damage and facilitate neurological complications during pregnancy.
Databáze: MEDLINE
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