Escherichia coli Sequence Type 457 Is an Emerging Extended-Spectrum-β-Lactam-Resistant Lineage with Reservoirs in Wildlife and Food-Producing Animals.
| Autor: | Nesporova K; CEITEC VFU Brno, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.; Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic., Wyrsch ER; The ithree institute, University of Technology Sydney, Sydney, New South Wales, Australia., Valcek A; CEITEC VFU Brno, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.; Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.; Faculty of Medicine, Biomedical Center, Charles University, Pilsen, Czech Republic., Bitar I; CEITEC VFU Brno, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.; Faculty of Medicine, Biomedical Center, Charles University, Pilsen, Czech Republic., Chaw K; Faculty of Medicine, University of Queensland, UQ Centre for Clinical Research, Brisbane, Australia.; Pathology Queensland, Brisbane, Australia., Harris P; Faculty of Medicine, University of Queensland, UQ Centre for Clinical Research, Brisbane, Australia.; Pathology Queensland, Brisbane, Australia., Hrabak J; Faculty of Medicine, Biomedical Center, Charles University, Pilsen, Czech Republic., Literak I; CEITEC VFU Brno, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.; Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic., Djordjevic SP; The ithree institute, University of Technology Sydney, Sydney, New South Wales, Australia., Dolejska M; CEITEC VFU Brno, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic monika.dolejska@gmail.com.; Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.; Faculty of Medicine, Biomedical Center, Charles University, Pilsen, Czech Republic. |
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| Jazyk: | angličtina |
| Zdroj: | Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Dec 16; Vol. 65 (1). Date of Electronic Publication: 2020 Dec 16 (Print Publication: 2020). |
| DOI: | 10.1128/AAC.01118-20 |
| Abstrakt: | Silver gulls carry phylogenetically diverse Escherichia coli , including globally dominant extraintestinal pathogenic E. coli (ExPEC) sequence types and pandemic ExPEC-ST131 clades; however, our large-scale study (504 samples) on silver gulls nesting off the coast of New South Wales identified E. coli ST457 as the most prevalent. A phylogenetic analysis of whole-genome sequences (WGS) of 138 ST457 samples comprising 42 from gulls, 2 from humans (Australia), and 14 from poultry farmed in Paraguay were compared with 80 WGS deposited in public databases from diverse sources and countries. E. coli ST457 strains are phylogenetic group F, carry fimH 145, and partition into five main clades in accordance to predominant flagella H-antigen carriage. Although we identified considerable phylogenetic diversity among the 138 ST457 strains, closely related subclades (<100 SNPs) suggested zoonotic or zooanthroponosis transmission between humans, wild birds, and food-producing animals. Australian human clinical and gull strains in two of the clades were closely related (≤80 SNPs). Regarding plasmid content, country, or country/source, specific connections were observed, including I1/ST23, I1/ST314, and I1/ST315 disseminating bla (Copyright © 2020 American Society for Microbiology.) |
| Databáze: | MEDLINE |
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