Development of a novel method to measure material surface staining by cigarette, e-cigarette or tobacco heating product aerosols.

Autor:	Dalrymple A; British American Tobacco, R&D, Southampton, Hampshire, SO15 8TL, UK., Badrock TC; Intertek Clinical Research Services, Hooton, Cheshire, CH66 7NZ, UK., Terry A; British American Tobacco, R&D, Southampton, Hampshire, SO15 8TL, UK., Bean EJ; British American Tobacco, R&D, Southampton, Hampshire, SO15 8TL, UK., Barber M; Borgwaldt KC GmbH Schnackenburgallee 15, 22525, Hamburg, Germany., Hall PJ; Intertek Clinical Research Services, Hooton, Cheshire, CH66 7NZ, UK., Coburn S; British American Tobacco, R&D, Southampton, Hampshire, SO15 8TL, UK., McAughey J; British American Tobacco, R&D, Southampton, Hampshire, SO15 8TL, UK., Murphy J; British American Tobacco, R&D, Southampton, Hampshire, SO15 8TL, UK.
Jazyk:	angličtina
Zdroj:	Heliyon [Heliyon] 2020 Sep 22; Vol. 6 (9), pp. e05012. Date of Electronic Publication: 2020 Sep 22 (Print Publication: 2020).
DOI:	10.1016/j.heliyon.2020.e05012
Abstrakt:	Tobacco smoke (CS) may visually stain indoor surfaces including ceilings, walls and soft furnishings over time. Potentially reduced risk products (PRRPs) such as e-cigarettes (EC) and tobacco heating products (THP) produce chemically less complex aerosols with significantly reduced levels of toxicants, particles and odour. However, the potential effects of EC and THP aerosols on the staining of indoor surfaces are currently unknown. In this study, an exposure chamber was developed as a model system to enable the accelerated staining of wallpaper and cotton samples by a scientific reference cigarette (3R4F), three THP (glo™, glo™ pro, glo™ sens) and an e-cigarette (iSwitch Maxx). Exposure to 3R4F reference cigarettes caused the greatest level of staining, which was significantly higher than glo™, glo™ pro, glo™ sens or iSwitch Maxx aerosols, all of which showed relatively little colour change. Exposure to 200-1000 puffs of 3R4F cigarette smoke resulted in a visible dose response effect to wallpaper and cotton samples which was not observed following exposure to glo™, glo™ pro, glo™ sens or iSwitch Maxx aerosols. Aging of the samples for 4 weeks post-exposure resulted in changes to the staining levels, however PRRP staining levels were minimal and significantly lower than 3R4F exposed samples. For the first time, diverse PRRPs across the tobacco and nicotine products risk continuum have been assessed in vitro for their impact on surface staining. CS exposure significantly increased the level of wallpaper and cotton staining, whereas exposure to glo™, glo™ pro, glo™ sens or iSwitch Maxx aerosols resulted in significantly reduced levels of staining, staining levels were also comparable to untreated control samples. (© 2020 The Author(s).)
Databáze:	MEDLINE
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