Acaricidal activity of (E)-cinnamaldehyde and α-bisabolol on populations of Rhipicephalus microplus (Acari: Ixodidae) with different resistance profiles.

Autor: Marchesini P; Programa de Pós-graduação em Ciências Veterinárias da Universidade Federal Rural do, Rio de Janeiro, BR-465, Km 7 - Seropédica, RJ, 23897-000, Brazil. Electronic address: paulabarrosocruz@hotmail.com., Novato TP; Programa de Pós-graduação em Ciências Veterinárias da Universidade Federal Rural do, Rio de Janeiro, BR-465, Km 7 - Seropédica, RJ, 23897-000, Brazil. Electronic address: tatinovatojf@gmail.com., Cardoso SJ; Programa de Pós-graduação em Ecologia da Universidade Federal de Juiz de Fora, Rua José Lourenço Kelmer, s/n - Campus Universitário, Juiz de Fora, MG, 36036-900, Brazil. Electronic address: simone.jcardoso@gmail.com., de Azevedo Prata MC; Embrapa Gado de Leite, Rua Eugênio do Nascimento, 610, Dom Bosco, Juiz de Fora, MG, 36038-330, Brazil. Electronic address: marcia.prata@embrapa.br., do Nascimento RM; Programa de Pós-graduação em Ciências Biológicas, Comportamento e Biologia Animal da Universidade Federal de Juiz de For a, Rua José Lourenço Kelmer, s/n - Campus Universitário, Juiz de Fora, MG, 36036-900, Brazil. Electronic address: rafael_mnascimento@yahoo.com.br., Klafke G; Centro de Pesquisa em Saúde Animal (IPVDF), Secretaria da Agricultura, Pecuária e Desenvolvimento Rural, Governo do Estado do Rio Grande do Sul, Estrada Municipal do Conde, 6000, Eldorado do Sul, RS, Brazil. Electronic address: guilherme-klafke@agricultura.rs.gov.br., Costa-Júnior LM; Departamento de Patologia, Universidade Federal do Maranhão, Av. dos Portugueses, 1966, Bacanga, São Luís, MA, CEP 65080-805, Brazil. Electronic address: livio.martins@ufma.br., Maturano R; Programa de Pós-graduação em Ciências Biológicas, Comportamento e Biologia Animal da Universidade Federal de Juiz de For a, Rua José Lourenço Kelmer, s/n - Campus Universitário, Juiz de Fora, MG, 36036-900, Brazil. Electronic address: ralphmaturano@gmail.com., Lopes WDZ; Departamento de Imunologia, Microbiologia, Parasitologia e Patologia, Instituto de Patologia Tropical e Saúde Pública da Universidade Federal de Goiás, Avenida Esperança, s/n, Campus Samambaia, Goiânia, GO, 74.690-900, Brazil. Electronic address: wdzlopes@hotmail.com., Bittencourt VREP; Programa de Pós-graduação em Ciências Veterinárias da Universidade Federal Rural do, Rio de Janeiro, BR-465, Km 7 - Seropédica, RJ, 23897-000, Brazil. Electronic address: vaniabit@gmail.com., Monteiro C; Departamento de Imunologia, Microbiologia, Parasitologia e Patologia, Instituto de Patologia Tropical e Saúde Pública da Universidade Federal de Goiás, Avenida Esperança, s/n, Campus Samambaia, Goiânia, GO, 74.690-900, Brazil. Electronic address: caiosat@gmail.com.
Jazyk: angličtina
Zdroj: Veterinary parasitology [Vet Parasitol] 2020 Oct; Vol. 286, pp. 109226. Date of Electronic Publication: 2020 Sep 04.
DOI: 10.1016/j.vetpar.2020.109226
Abstrakt: This study aimed to investigate the acaricidal activity of (E)-cinnamaldehyde and α-bisabolol on populations of Rhipicephalus microplus with different resistance profiles. The adult immersion test (AIT) was used to characterize the susceptibility of tick populations (50 field populations) to synthetic acaricides: deltamethrin, amitraz, and chlorfenvinphos. The larval packet test (LPT) was used to determine the LC 50 values for (E)-cinnamaldehyde (populations 1-25) and α-bisabolol (populations 26-50) at the concentrations of 0.31, 0.62, 1.25, 2.0, 2.5, 5.0 and 10.0 mg/mL. The susceptible strain Porto Alegre (POA) was used as a reference for calculating the resistance ratio (RR). In the AIT, deltamethrin did not show efficacy >95 % for any of the populations, whereas amitraz and chlorfenvinphos have presented efficacy >95 % for three (6 %) and 15 (30 %) populations, respectively. In the LPT, the LC 50 values of (E)-cinnamaldehyde and α-bisabolol varied from 0.23 to 2.36 mg/mL and 1.57-3.01 mg/mL, respectively. The RR 50 for (E)-cinnamaldehyde showed 20 (80 %) populations with values <1.0 and no population with values>1.5. As for α-bisabolol, only two (8%) populations have presented RR 50 <1.0, whereas three (12 %) populations showed incipient resistance to this sesquiterpene (RR 50 between 1.5 and 2.0). The results indicate that all studied tick populations showed low susceptibility to at least one of the commercial acaricides tested. In addition, comparison between the LC 50 values of (E)-cinnamaldehyde and α-bisabolol for the field populations and the susceptible strain POA suggests that there is no cross-resistance of (E)-cinnamaldehyde and α-bisabolol for the tick populations evaluated, and that the differences in the LC 50 values are due to population variations.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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