Fully self-gated free-running 3D Cartesian cardiac CINE with isotropic whole-heart coverage in less than 2 min.

Autor: Küstner T; School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London, UK., Bustin A; School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London, UK., Jaubert O; School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London, UK., Hajhosseiny R; School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London, UK., Masci PG; School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London, UK., Neji R; School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London, UK.; MR Research Collaborations, Siemens Healthcare Limited, Frimley, UK., Botnar R; School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London, UK.; Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile., Prieto C; School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London, UK.; Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile.
Jazyk: angličtina
Zdroj: NMR in biomedicine [NMR Biomed] 2021 Jan; Vol. 34 (1), pp. e4409. Date of Electronic Publication: 2020 Sep 25.
DOI: 10.1002/nbm.4409
Abstrakt: Purpose: To develop a novel fast water-selective free-breathing 3D Cartesian cardiac CINE scan with full self-navigation and isotropic whole-heart (WH) coverage.
Methods: A free-breathing 3D Cartesian cardiac CINE scan with a water-selective balanced steady-state free precession and a continuous (non-ECG-gated) variable-density Cartesian sampling with spiral profile ordering, out-inward sampling and acquisition-adaptive alternating tiny golden and golden angle increment between spiral arms is proposed. Data is retrospectively binned based on respiratory and cardiac self-navigation signals. A translational respiratory-motion-corrected and cardiac-motion-resolved image is reconstructed with a multi-bin patch-based low-rank reconstruction (MB-PROST) within about 15 min. A respiratory-motion-resolved approach is also investigated. The proposed 3D Cartesian cardiac CINE is acquired in sagittal orientation in 1 min 50 s for 1.9 mm 3 isotropic WH coverage. Left ventricular (LV) function parameters and image quality derived from a blinded reading of the proposed 3D CINE framework are compared against conventional multi-slice 2D CINE imaging in 10 healthy subjects and 10 patients with suspected cardiovascular disease.
Results: The proposed framework provides free-breathing 3D cardiac CINE images with 1.9 mm 3 spatial and about 45 ms temporal resolution in a short acquisition time (<2 min). LV function parameters derived from 3D CINE were in good agreement with 2D CINE (10 healthy subjects and 10 patients). Bias and confidence intervals were obtained for end-systolic volume, end-diastolic volume and ejection fraction of 0.1 ± 3.5 mL, -0.6 ± 8.2 mL and -0.1 ± 2.2%, respectively.
Conclusion: The proposed framework enables isotropic 3D Cartesian cardiac CINE under free breathing for fast assessment of cardiac anatomy and function.
(© 2020 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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