Autor: |
Pegorari MS; Universidade Federal do Amapá - Unifap, Macapá, AP, Brasil., Matos AP; Universidade Federal do Amapá - Unifap, Macapá, AP, Brasil., Iosimuta NCR; Universidade Federal do Amapá - Unifap, Macapá, AP, Brasil., Ferreira VTK; Universidade Federal do Amapá - Unifap, Macapá, AP, Brasil., Ohara DG; Universidade Federal do Amapá - Unifap, Macapá, AP, Brasil., Santos EPR; Universidade Federal do Amapá - Unifap, Macapá, AP, Brasil., Silva CFR; Universidade Federal do Amapá - Unifap, Macapá, AP, Brasil., Santos NLOD; Universidade Federal do Amapá - Unifap, Macapá, AP, Brasil., Rocha AP; Universidade Federal de São Paulo - Unifesp, São Paulo, SP, Brasil., Atallah ÁN; Universidade Federal de São Paulo - Unifesp, São Paulo, SP, Brasil., Pinto ACPN; Universidade Federal do Amapá - Unifap, Macapá, AP, Brasil.; Universidade Federal de São Paulo - Unifesp, São Paulo, SP, Brasil. |
Abstrakt: |
The aim of this rapid systematic review is to analyze the prevalence of clinical, socioeconomic, and demographic characteristics, laboratory and imaging findings, diagnostic tests, and treatment information of older adults with COVID-19. To conduct this systematic review, the Cochrane Handbook recommendations will be followed. Patients aged 60 years or older with a confirmed diagnosis of SARS-CoV-2 infection will be included. A comprehensive literature search will be performed in the following databases: MEDLINE via PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Latin American and Caribbean Health Sciences Literature (LILACS), Spanish Bibliographic Index on Health Sciences (IBECS) and Epistemonikos COVID-19 L·OVE platform. No language restrictions will be applied. To assess the methodological quality of the included studies and the certainty of the evidence, the Newcastle-Ottawa Scale, and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach will be used. The meta-analysis will be performed using R software. We believe this rapid systematic review will be able to summarize the currently available evidence on clinical, socioeconomic characteristics, and management of COVID-19 in older adults. Therefore, it will help implement adequate strategies to fight the pandemic and assist in understanding the clinical profile of older patients with COVID-19, providing data with due scientific support upon which to base future choices of procedures and interventions. |