Management of Dyslipidemia for Cardiovascular Disease Risk Reduction: Synopsis of the 2020 Updated U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline.

Autor:	O'Malley PG; Uniformed Services University of the Health Sciences, Bethesda, Maryland (P.G.O., M.J.A., B.E.N.)., Arnold MJ; Uniformed Services University of the Health Sciences, Bethesda, Maryland (P.G.O., M.J.A., B.E.N.)., Kelley C; U.S. Department of Veterans Affairs Pharmacy Benefits Management Services, Scottsdale, Arizona (C.K.)., Spacek L; South Texas Veterans Health Care System and University of Texas Health Science Center, San Antonio, Texas (L.S., J.R.D.)., Buelt A; Bay Pines VA Healthcare System, Bay Pines, Florida (A.B.)., Natarajan S; New York University School of Medicine and VA New York Harbor Healthcare System, New York, New York (S.N.)., Donahue MP; Duke University Medical Center and Durham VA Medical Center, Durham, North Carolina (M.P.D.)., Vagichev E; Walter Reed National Military Medical Center, Bethesda, Maryland (E.V., L.T.)., Ballard-Hernandez J; Tibor Rubin VA Medical Center, Long Beach, California (J.B.)., Logan A; Cincinnati VA Medical Center, Cincinnati, Ohio (A.L.)., Thomas L; Walter Reed National Military Medical Center, Bethesda, Maryland (E.V., L.T.)., Ritter J; Walter Reed Military Medical Center and Uniformed Services University of the Health Sciences, Bethesda, Maryland (J.R.)., Neubauer BE; Uniformed Services University of the Health Sciences, Bethesda, Maryland (P.G.O., M.J.A., B.E.N.)., Downs JR; South Texas Veterans Health Care System and University of Texas Health Science Center, San Antonio, Texas (L.S., J.R.D.).
Jazyk:	angličtina
Zdroj:	Annals of internal medicine [Ann Intern Med] 2020 Nov 17; Vol. 173 (10), pp. 822-829. Date of Electronic Publication: 2020 Sep 22.
DOI:	10.7326/M20-4648
Abstrakt:	Description: In June 2020, the U.S. Department of Veterans Affairs (VA) and U.S. Department of Defense (DoD) released a joint update of their clinical practice guideline for managing dyslipidemia to reduce cardiovascular disease risk in adults. This synopsis describes the major recommendations. Methods: On 6 August to 9 August 2019, the VA/DoD Evidence-Based Practice Work Group (EBPWG) convened a joint VA/DoD guideline development effort that included clinical stakeholders and conformed to the Institute of Medicine's tenets for trustworthy clinical practice guidelines. The guideline panel developed key questions, systematically searched and evaluated the literature (English-language publications from 1 December 2013 to 16 May 2019), and developed 27 recommendations and a simple 1-page algorithm. The recommendations were graded by using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) system. Recommendations: This synopsis summarizes key features of the guideline in 7 crucial areas: targeting of statin dose (not low-density lipoprotein cholesterol goals), additional tests for risk prediction, primary and secondary prevention, laboratory testing, physical activity, and nutrition.
Databáze:	MEDLINE
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