Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation.

Autor: Galand V; LTSI-UMR 1099, INSERM, Service de Cardiologie et Maladies Vasculaires, CHU de Rennes, Université de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France. Electronic address: vincent.galand35@gmail.com., Flécher E; LTSI-UMR 1099, INSERM, Service de Cardiologie et Maladies Vasculaires, CHU de Rennes, Université de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France., Chabanne C; LTSI-UMR 1099, INSERM, Service de Cardiologie et Maladies Vasculaires, CHU de Rennes, Université de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France., Lelong B; LTSI-UMR 1099, INSERM, Service de Cardiologie et Maladies Vasculaires, CHU de Rennes, Université de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France., Goéminne C; Cardiac Intensive Care Unit, Department of Cardiology, Department of Cardiac Surgery, Institut Coeur-Poumons, CHU de Lille, 59000 Lille, France., Vincentelli A; Cardiac Intensive Care Unit, Department of Cardiology, Department of Cardiac Surgery, Institut Coeur-Poumons, CHU de Lille, 59000 Lille, France., Delmas C; CHU de Toulouse, 31300 Toulouse, France., Dambrin C; CHU de Toulouse, 31300 Toulouse, France., Nubret K; LIRYC Institute, Hôpital Cardiologique du Haut-Lévêque, Université de Bordeaux, 33600 Pessac, France., Pernot M; LIRYC Institute, Hôpital Cardiologique du Haut-Lévêque, Université de Bordeaux, 33600 Pessac, France., Kindo M; Department of Cardiovascular Surgery, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France., Hoang Minh T; Department of Cardiovascular Surgery, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France., Gaudard P; Department of Anaesthesiology, Critical Care Medicine and Cardiac Surgery, Hôpital Arnaud de Villeneuve, CHU de Montpellier, Université de Montpellier, PhyMedExp, INSERM, CNRS, 34090 Montpellier, France., Frapier JM; Department of Anaesthesiology, Critical Care Medicine and Cardiac Surgery, Hôpital Arnaud de Villeneuve, CHU de Montpellier, Université de Montpellier, PhyMedExp, INSERM, CNRS, 34090 Montpellier, France., Michel M; Department of Cardiology and Heart Transplantation Unit, CHU de Nantes, 44093 Nantes, France., Sénage T; Department of Cardiology and Heart Transplantation Unit, CHU de Nantes, 44093 Nantes, France., Boignard A; Department of Cardiology and Cardiovascular Surgery, Hôpital Albert Michallon, CHU de Grenoble, 38700 La Tronche, France., Chavanon O; Department of Cardiology and Cardiovascular Surgery, Hôpital Albert Michallon, CHU de Grenoble, 38700 La Tronche, France., Verdonk C; Department of Cardiology and Cardiac Surgery, Hôpital Bichat, 75018 Paris, France., Para M; Department of Cardiology and Cardiac Surgery, Hôpital Bichat, 75018 Paris, France., Pelcé E; Department of Cardiac Surgery, Hôpital de la Timone, 13005 Marseille, France., Gariboldi V; Department of Cardiac Surgery, Hôpital de la Timone, 13005 Marseille, France., Pozzi M; Department of Cardiac Surgery, Hôpital Cardio-Vasculaire Louis Pradel, 69500 Bron, France., Obadia JF; Department of Cardiac Surgery, Hôpital Cardio-Vasculaire Louis Pradel, 69500 Bron, France., Litlzer PY; Department of Cardiology and Cardiovascular Surgery, Hôpital Charles Nicolle, 76000 Rouen, France., Anselme F; Department of Cardiology and Cardiovascular Surgery, Hôpital Charles Nicolle, 76000 Rouen, France., Babatasi G; Department of Cardiology and Cardiac Surgery, Université de Caen and CHU de Caen, 14000 Caen, France., Plane AF; Department of Cardiology and Cardiac Surgery, Université de Caen and CHU de Caen, 14000 Caen, France., Garnier F; Department of Cardiology and Cardiac Surgery, CHU de Dijon, 21000 Dijon, France., Bielefeld M; Department of Cardiology and Cardiac Surgery, CHU de Dijon, 21000 Dijon, France., Hamon D; Department of Cardiology and Cardiac Surgery, Hôpital Henri Mondor, AP-HP, 94010 Créteil, France., Radu C; Department of Cardiology and Cardiac Surgery, Hôpital Henri Mondor, AP-HP, 94010 Créteil, France., Bourguignon T; Department of Cardiology and Cardiac Surgery, CHRU de Tours, 37000 Tours, France., Genet T; Department of Cardiology and Cardiac Surgery, CHRU de Tours, 37000 Tours, France., Eschalier R; Cardiology Department, CHU de Clermont-Ferrand, 63000 Clermont-Ferrand, France., D'Ostrevy N; Cardiology Department, CHU de Clermont-Ferrand, 63000 Clermont-Ferrand, France., Bories MC; Cardiology Department, Hôpital Européen Georges-Pompidou, AP-HP, 75015 Paris, France., Marijon E; Cardiology Department, Hôpital Européen Georges-Pompidou, AP-HP, 75015 Paris, France., Vanhuyse F; Department of Cardiology and Cardiac Surgery, Hopital de Brabois, CHU de Nancy, 54500 Vandœuvre-lès-Nancy, France., Blangy H; Department of Cardiology and Cardiac Surgery, Hopital de Brabois, CHU de Nancy, 54500 Vandœuvre-lès-Nancy, France., Leclercq C; LTSI-UMR 1099, INSERM, Service de Cardiologie et Maladies Vasculaires, CHU de Rennes, Université de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France., Martins RP; LTSI-UMR 1099, INSERM, Service de Cardiologie et Maladies Vasculaires, CHU de Rennes, Université de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.
Jazyk: angličtina
Zdroj: Archives of cardiovascular diseases [Arch Cardiovasc Dis] 2020 Nov; Vol. 113 (11), pp. 701-709. Date of Electronic Publication: 2020 Sep 17.
DOI: 10.1016/j.acvd.2020.05.018
Abstrakt: Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.
Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years) receiving an LVAD.
Methods: This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups-younger (aged<70 years) and elderly (aged≥70 years), based on age at time of LVAD implantation.
Results: A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged≥70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0-15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. Lastly, when compared with younger patients implanted as destination therapy, the elderly group also exhibited similar mid-term survival.
Conclusion: This work strongly suggests that selected elderly adults can be scheduled for LVAD implantation.
(Copyright © 2020 Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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