Biological Evaluation of Essential Oils from Selected Medicinal Plants and Their Main Components against Phytomonas davidi (Kinetoplastea: Trypanosomatidae).

Autor: Guzmán M; Facultad de Medicina, Universidad Autónoma de Madrid (UAM), Arzobispo, Morcillo 4, 28029, Madrid, Spain.; Instituto de Ciencias Agrarias, CSIC, Serrano 115-dpdo, 28006, Madrid, Spain., González-Coloma A; Instituto de Ciencias Agrarias, CSIC, Serrano 115-dpdo, 28006, Madrid, Spain., Fe Andrés M; Instituto de Ciencias Agrarias, CSIC, Serrano 115-dpdo, 28006, Madrid, Spain., Navarro-Rocha J; Centro de Investigación y Tecnología Agroalimentaria de, Aragón (CITA), Av. Montañana 930, 50059, Zaragoza, Spain., Martínez-Díaz RA; Facultad de Medicina, Universidad Autónoma de Madrid (UAM), Arzobispo, Morcillo 4, 28029, Madrid, Spain.
Jazyk: angličtina
Zdroj: Chemistry & biodiversity [Chem Biodivers] 2020 Oct; Vol. 17 (10), pp. e2000521. Date of Electronic Publication: 2020 Sep 18.
DOI: 10.1002/cbdv.202000521
Abstrakt: Eight essential oils (EOs) from selected medicinal plants have been tested for their activity against Phytomonas davidi, a plant trypanosomal parasite. In the present research, the EOs have been tested on promastigote forms of P. davidi ATCC ® 30287™ strain, along with their major components, both separately and in binary combinations, using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction assay. The EOs with the highest antipromastigote activity were from Origanum virens and Salvia lavandulifolia. Thymol and β-pinene were the most active pure compounds. The study of the activity of the pure compounds in combination indicated the existence of antagonistic and synergistic effects depending on the concentration tested. In general, the combinations at low concentrations favored the activity.
(© 2020 Wiley-VHCA AG, Zurich, Switzerland.)
Databáze: MEDLINE
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