Association Between Psoriasis and Depression: A Traditional Review.

Autor: Sahi FM; Dermatology, California Institute of Behavioural Neurosciences and Psychology, Fairfield, USA., Masood A; General Surgery, California Institute of Behavioural Neurosciences and Psychology, Fairfield, USA., Danawar NA; General Surgery, California Institute of Behavioural Neurosciences and Psychology, Fairfield, USA., Mekaiel A; Internal Medicine, California Institute of Behavioural Neurosciences and Psychology, Fairfield, USA., Malik BH; Internal Medicine, California Institute of Behavioural Neurosciences and Psychology, Fairfield, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2020 Aug 13; Vol. 12 (8), pp. e9708. Date of Electronic Publication: 2020 Aug 13.
DOI: 10.7759/cureus.9708
Abstrakt: Psoriasis is a chronic inflammatory disease of the skin with multiple comorbidities, depression being one of them. Psoriasis affects the personal, social, and sexual lives of the patients resulting in psychological strain.  Psoriasis and depression amplify each other. Supporting evidence has proven multiple common mechanisms between the two diseases: inflammatory overlap, genetic evidence, low vitamin D3, and melatonin levels are common in both psoriasis and depression. Fear of social rejection and self-stigmatization act as a fuel to fire inflaming depression in psoriatic patients. The study explains the link between psoriasis and depression and their effects on quality of life. There is a need to highlight the importance of addressing the psychological effects of psoriasis along with its physical aspects for better treatment outcomes.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2020, Sahi et al.)
Databáze: MEDLINE