Antimicrobial prophylaxis is considered sufficient to preserve an acceptable surgical site infection rate in clean orthopaedic and neurosurgeries in dogs.
Autor: | Välkki KJ; Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 57, Viikintie 49, 00014, Helsinki, Finland. kirsi.valkki@helsinki.fi., Thomson KH; Small Animal Hospital, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 57, Viikintie 49, 00014, Helsinki, Finland., Grönthal TSC; Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 57, Viikintie 49, 00014, Helsinki, Finland., Junnila JJT; Oy 4Pharma Ltd, Arkadiankatu 7, 00100, Helsinki, Finland., Rantala MHJ; Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 57, Viikintie 49, 00014, Helsinki, Finland., Laitinen-Vapaavuori OM; Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 57, Viikintie 49, 00014, Helsinki, Finland., Mölsä SH; Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 57, Viikintie 49, 00014, Helsinki, Finland. |
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Jazyk: | angličtina |
Zdroj: | Acta veterinaria Scandinavica [Acta Vet Scand] 2020 Sep 17; Vol. 62 (1), pp. 53. Date of Electronic Publication: 2020 Sep 17. |
DOI: | 10.1186/s13028-020-00545-z |
Abstrakt: | Background: Surgical site infections (SSI) are associated with increased morbidity and mortality. To lower the incidence of SSI, antimicrobial prophylaxis is given 30-60 min before certain types of surgeries in both human and veterinary patients. However, due to the increasing concern of antimicrobial resistance, the benefit of antimicrobial prophylaxis in clean orthopaedic and neurosurgeries warrants investigation. The aims of this retrospective cross-sectional study were to review the rate of SSI and evaluate the compliance with antimicrobial guidelines in dogs at a veterinary teaching hospital in 2012-2016. In addition, possible risk factors for SSI were assessed. Results: Nearly all dogs (377/406; 92.9%) received antimicrobial prophylaxis. Twenty-nine dogs (7.1%) did not receive any antimicrobials and only four (1.1%) received postoperative antimicrobials. The compliance with in-house and national protocols was excellent regarding the choice of prophylactic antimicrobial (cefazolin), but there was room for improvement in the timing of prophylaxis administration. Follow-up data was available for 89.4% (363/406) of the dogs. Mean follow-up time was 464 days (range: 3-2600 days). The overall SSI rate was 6.3%: in orthopaedic surgeries it was 6.7%, and in neurosurgeries it was 4.2%. The lowest SSI rates (0%) were seen in extracapsular repair of cranial cruciate ligament rupture, ulnar ostectomy, femoral head and neck excision, arthrotomy and coxofemoral luxation repair. The highest SSI rate (25.0%) was seen in arthrodesis. Omission of antimicrobials did not increase the risk for SSI (P = 0.56; OR 1.7; CI Conclusions: Antimicrobial prophylaxis without postoperative antimicrobials is sufficient to maintain the overall rate of SSI at a level similar to published data in canine clean orthopedic and neurosurgeries. |
Databáze: | MEDLINE |
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