Metabolic Reprogramming is a Hallmark of Metabolism Itself.

Autor: Medina MÁ; Andalucía Tech, Facultad de Ciencias, Departamento de Biología Molecular y Bioquímica, and IBIMA (Biomedical Research Institute of Málaga), Universidad de Málaga, Málaga, E-29071, Spain.; CIBER de Enfermedades Raras (CIBERER), Málaga, E-29071, Spain.
Jazyk: angličtina
Zdroj: BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2020 Oct; Vol. 42 (10), pp. e2000058. Date of Electronic Publication: 2020 Sep 17.
DOI: 10.1002/bies.202000058
Abstrakt: The reprogramming of metabolism has been identified as one of the hallmarks of cancer. It is becoming more and more frequent to connect other diseases with metabolic reprogramming. This article aims to argue that metabolic reprogramming is not driven by disease but instead is the main hallmark of metabolism, based on its dynamic behavior that allows it to continuously adapt to changes in the internal and external conditions.
(© 2020 Wiley Periodicals LLC.)
Databáze: MEDLINE
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