HEllenic Registry on Myocarditis SyndromES on behalf of Hellenic Heart Failure Association: The HERMES-HF Registry.

Autor: Adamopoulos S; Heart Failure and Transplant Unit, Onassis Cardiac Surgery Centre, 356 Syngrou Avenue, 176 74 Kallithea, Athens, Greece., Miliopoulos D; Heart Failure and Transplant Unit, Onassis Cardiac Surgery Centre, 356 Syngrou Avenue, 176 74 Kallithea, Athens, Greece., Karavidas A; Cardiology Department, General Hospital 'G. Gennimatas', Athens, Greece., Nikolaou M; Cardiology Department, General Hospital 'Sismanogleio-Amalia Fleming', Athens, Greece., Lazaros G; 1st Cardiology Clinic, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece., Gkouziouta A; Heart Failure and Transplant Unit, Onassis Cardiac Surgery Centre, 356 Syngrou Avenue, 176 74 Kallithea, Athens, Greece., Manginas A; Interventional Cardiology and Cardiology Department, Mediterraneo Hospital, Athens, Greece., Sevastos G; Interventional Cardiology and Cardiology Department, Mediterraneo Hospital, Athens, Greece., Karvounis H; 1st Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece., Karamitsos TD; 1st Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece., Hahalis G; Department of Cardiology, University of Patras Medical School, Patras, Greece., Leopoulou M; Department of Cardiology, University of Patras Medical School, Patras, Greece., Grigoriou K; Department of Cardiology, 'Elpis' General Hospital of Athens, Athens, Greece., Balta D; Cardiology Department, General Hospital 'G. Gennimatas', Athens, Greece., Avgeropoulou CC; Cardiology Department, Hippokration Hospital, Athens, Greece., Kasiakogias A; 1st Cardiology Clinic, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece., Mantas I; Department of Cardiology, General Hospital of Chalkida, Chalkida, Greece., Daskalopoulos N; Department of Cardiology, General Hospital of Chalkida, Chalkida, Greece., Varvarousis D; Department of Cardiology, General Hospital of Chalkida, Chalkida, Greece., Parthenakis FI; Department of Cardiology, Heraklion University Hospital, Iraklio, Greece., Patrianakos AP; Department of Cardiology, Heraklion University Hospital, Iraklio, Greece., Patsilinakos S; Department of Cardiology, Konstantopoulio General Hospital, Athens, Greece., Karanikas S; Department of Cardiology, Konstantopoulio General Hospital, Athens, Greece., Konstantinides SV; Department of Cardiology, Democritus University of Thrace, Alexandroupolis, Greece., Tziakas DN; Department of Cardiology, Democritus University of Thrace, Alexandroupolis, Greece., Kouvelas N; Department of Cardiology, 251 Airforce General Hospital, Athens, Greece., Ntoliou P; Department of Cardiology, 251 Airforce General Hospital, Athens, Greece., Manolis AJ; Department of Cardiology, Asklepeion General Hospital, Athens, Greece., Tsinivizov P; Department of Cardiology, Asklepeion General Hospital, Athens, Greece., Iliodromitis EK; 2nd Department of Cardiology, Attikon University Hospital, University of Athens, Athens, Greece., Vrettou AR; 2nd Department of Cardiology, Attikon University Hospital, University of Athens, Athens, Greece., Kakouros SN; Department of Cardiology, Sismanogleio General Hospital, Athens, Greece., Douras A; Department of Cardiology, Achillopouleio General Hospital, Volos, Greece., Mpaka N; Department of Cardiology, Achillopouleio General Hospital, Volos, Greece., Makridis P; Cardiology Department, General Hospital of Edessa, Edessa, Greece., Karapatsoudi E; Cardiology Department, General Hospital of Edessa, Edessa, Greece., Papoulidis N; Cardiology Department, General Hospital of Kavala, Kavala, Greece., Sideris A; Laboratory of Cardiac Electrophysiology, 'Evangelismos' General Hospital of Athens, Athens, Greece., Parissis JT; 2nd Department of Cardiology, Attikon University Hospital, University of Athens, Athens, Greece., Triposkiadis F; Department of Cardiology, University General Hospital of Larissa, Larissa, Greece., Trikas A; Department of Cardiology, 'Elpis' General Hospital of Athens, Athens, Greece., Filippatos G; 2nd Department of Cardiology, Attikon University Hospital, University of Athens, Athens, Greece.
Jazyk: angličtina
Zdroj: ESC heart failure [ESC Heart Fail] 2020 Dec; Vol. 7 (6), pp. 3676-3684. Date of Electronic Publication: 2020 Sep 16.
DOI: 10.1002/ehf2.12894
Abstrakt: Aims: Despite the existence of many studies, there are still limited data about the characteristics of myocarditis in Greece. This led to the creation of the Greek Myocarditis Registry aiming to document the different symptoms and treatment of myocarditis, assess possible prognostic factors, and find similarities and differences to what is already published in literature. This paper is a preliminary descriptive analysis of this Registry.
Methods and Results: We analysed data for the hospitalization period of all patients included in the Registry from December 2015 until November 2017. Statistics are reported as frequency (%) or median and inter-quartile range (IQR) as appropriate. In total, 146 patients were included; 83.3% of the patients reported an infection during the last 3 months. The most common symptom, regardless of the underlying infection, was chest pain (82.2%) followed by dyspnoea (18.5%), while the most common finding in clinical examination was tachycardia (26.7%). Presentation was more frequent in the winter months. ECG findings were not specific, with the repolarization abnormalities being the most frequent (60.3%). Atrial fibrillation was observed in two patients, both of whom presented with a reduced ventricular systolic function. Left ventricular ejection fraction changed significantly during the hospitalization [55% (IQR: 50-60%) on admission vs. 60% (IQR: 55-60%) on discharge, P = 0.0026]. Cardiac magnetic resonance was performed in 88 patients (61%), revealing mainly subepicardial and midcardial involvement of the lateral wall. Late gadolinium enhancement was present in all patients, while oedema was found in 39 of them. Only 11 patients underwent endomyocardial biopsy. Discharge medication consisted mainly of beta-blockers (71.9%) and angiotensin-converting enzyme inhibitors (41.8%), while 39.7% of the patients were prescribed both.
Conclusions: This preliminary analysis describes the typical presentation of myocarditis patients in Greece. It is a first step in developing a better prognostic model for the course of the disease, which will be completed after the incorporation of the patients' follow-up data.
(© 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology.)
Databáze: MEDLINE
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