Bone augmentation by replica-based bone formation.

Autor: Draenert ME; Department of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians University, Munich, Germany. Electronic address: mdraener@dent.med.uni-muenchen.de., Martini C; Clinic of Oral and Maxillofacial Surgery, Private Practice for Oral & Maxillofacial Surgery, Nymphenburgerstrasse 148, 80634, Munich, Germany. Electronic address: info@mkg-rotkreuzplatz.de., Watts DC; School of Medical Sciences and Photon Science Institute, University of Manchester, Oxford Road, Manchester M139PL UK. Electronic address: david.watts@manchester.ac.uk., Draenert K; Center of Orthopedic Research, Gabriel-Max-Strasse 3, 81545, Munich, Germany. Electronic address: k.draenert@zow.ch., Wittig-Draenert A; Center of Orthopedic Research, Gabriel-Max-Strasse 3, 81545, Munich, Germany. Electronic address: alice.draenert@gmx.net.
Jazyk: angličtina
Zdroj: Dental materials : official publication of the Academy of Dental Materials [Dent Mater] 2020 Nov; Vol. 36 (11), pp. 1388-1396. Date of Electronic Publication: 2020 Sep 12.
DOI: 10.1016/j.dental.2020.08.005
Abstrakt: Objective: The sources of iliac crest bone grafts are limited. Alternatives are evaluated due to the progress in biomaterial sciences. Synthetical hydroxyapatite (HA), ß-tricalcium phosphate (ß-TCP) or biphasic compounds, or even a mélange of HA and ß-TCP will replace bovine ceramics. The goal is maintenance of replica-based-bone formation (RBBF) for bone augmentation.
Methods: 2 female and 2 male patients between 41 and 73 years with 5 sinus elevations were evaluated. Sinus elevations with lateral fenestration, trapezoidal-muco-periosteal flaps and filling with micro-chambered beads (1.5 mm) was performed. A porcine-collagenous membrane and the refixated flap covered the defect. A biopsy program over 20 months was confirm confirm the maintenance of the newly formed bone.
Results: A fast bone formation was pronounced. The biopsies revealed mature lamellar bone and full osseointegration of the ß-TCP implant. The biopsy after 20 months showed compact bone with osseointegration of minor rests of the ceramic implant. The defect revealed a mature bone stock already after 5 weeks.
Significance: The introduction of the replica-based-bone formation (RBBF) around micro-chambered beads will change the paradigm of bone augmentation. The next step of the ongoing study has to redefine the interval for implant insertion. The clinical approach confirms the breakthrough to primary mature lamellar bone formation and will permit reduction of placement time for a dental implant.
(Copyright © 2020 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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