Chronic Kidney Disease in Iran: First Report of the National Registry in Children and Adolescences.

Autor: Ataei N; Pediatric Chronic Kidney Disease Research Center, Department of Pediatric Nephrology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran . ataiinem@tums.ac.ir., Madani A; Pediatric Chronic Kidney Disease Research Center, Department of Pediatric Nephrology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran., Esfahani ST; Pediatric Chronic Kidney Disease Research Center, Department of Pediatric Nephrology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran., Otoukesh H; Ali-Asghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran., Hooman N; Ali-Asghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran., Hoseini R; Ali-Asghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran., Fazel M; Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran., Derakhshan A; Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Gheissari A; Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran., Sorkhi H; Non-Communicable Pediatric Diseases Research Center, Department of Pediatric Nephrology, Amirkola Children Hospital, Babol University of Medical Sciences, Babol, Iran., Abbasi A; Pediatric Chronic Kidney Disease Research Center, Department of Pediatric Nephrology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran., Fahimi D; Bahrami Children's Hospital, Tehran University of Medical Sciences, Tehran, Iran., Ghane Sharbaf F; Sheikh Children's Hospital, Mashhad University of Medical Sciences, Mashhad, Iran., Mortazavi F; Department of Pediatrics, Tabriz University of Medical Sciences Tabriz, Iran., Falakaflaki B; Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran., Nikibakhsh AA; Urmia University of Medical Sciences, Urmia, Iran., Sadeghi Bojd S; Department of Pediatrics, Zahedan University of Medical Sciences, Zahedan, Iran., Hosseini Tabatabaei SMT; Department of Pediatrics, Zahedan University of Medical Sciences, Zahedan, Iran., Ghasemi K; Department of Pediatrics Nephrology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran., Ahmadzadeh A; Abozar Hospital, Ahvaz Jondishapour University of Medical Sciences, Ahvaz, Iran., Yousefichaijan P; Amirkabir Hospital, Arak University of Medical Sciences, Arak, Iran., Safaei Asl A; Department of Pediatrics, Guilan University of Medical Sciences, Guilan, Iran., Safaeian B; Taleghani Pediatric Hospital, Golestan University of Medical Sciences, Gorgan, Iran., Khazaei S; Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran., Hejazipour L; Pediatric Chronic Kidney Disease Research Center, Department of Pediatric Nephrology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran., Seyed Zadeh A; Razi Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran., Ataei F; Pediatric Chronic Kidney Disease Research Center, Department of Pediatric Nephrology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Jazyk: angličtina
Zdroj: Urology journal [Urol J] 2020 Sep 13; Vol. 18 (1), pp. 122-130. Date of Electronic Publication: 2020 Sep 13.
DOI: 10.22037/uj.v16i7.5759
Abstrakt: Purpose: Knowing the epidemiological aspects of chronic kidney disease (CKD) in children is crucial for early recognition, identification of reversible causes, and prognosis. Here, we report the epidemiological characteristics of childhood CKD in Iran.
Materials and Methods: This cross-sectional study was conducted during 1991 - 2009. The data were collected using the information in the Iranian Pediatric Registry of Chronic Kidney Disease (IPRCKD) core dataset.
Results: A total of 1247 children were registered. The mean age of the children at registration was 0.69 ± 4.72 years (range, 0.25 -18 years), 7.79 ± 3.18 years for hemodialysis (HD), 4.24 ± 1.86 years for continuous ambulatory peritoneal dialysis (CAPD), and 3.4±1.95 years for the children who underwent the renal transplantation (RT) (P < .001). The mean year of follow-up was 7.19 ± 4.65 years. The mean annual incidence of CKD 2-5 stages was 3.34 per million age-related population (pmarp). The mean prevalence of CKD 2-5 stages was 21.95 (pmarp). The cumulative 1-, 5-, and 10-year patients' survival rates were 98.3%, 90.7%, and 84.8%, respectively. The etiology of the CKD included the congenital anomalies of the kidney and urinary tract (CAKUT) (40.01%), glomerulopathy (19.00%), unknown cause (18.28%), and cystic/hereditary/congenital disease (11.14%).
Conclusion: The incidence and prevalence rate of pediatric CKD in Iran is relatively lower than those reported in Europe and other similar studies. CAKUT was the main cause of the CKD. Appropriate management of CAKUT including early urological intervention is required to preserve the renal function. Herein, the long-term survival rate was higher among the children with CKD than the literature.
Databáze: MEDLINE
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