| Autor: |
Alavi Foumani A; Inflammatory Lung Disease Research Center, Department of Internal Medicine, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran., Yaghubi Kalurazi T; Department of Health, Nutrition and Infectious Diseases, School of Medicine Guilan University of Medical Sciences, Rasht, Iran., Mohammadzadeh Rostami F; Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran., Sedigh Ebrahim-Saraie H; Razi Clinical Research Development Center, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran., Nazari-Alam A; Department of Microbiology, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran., Halaji M; Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. |
| Abstrakt: |
The present study aims to investigate the prevalence of Pseudomonas aeruginosa in Iranian Cystic Fibrosis (CF) patients. We conducted a systematic search on this topic in Web of Science, PubMed, Embase, Scopus, and Google Scholar electronic databases to the end of July 2019. Then, 14 articles with eligible criteria were selected for data extraction and analysis by Comprehensive Meta-Analysis Software. The pooled prevalence of P. aeruginosa was 40.6% (95% CI: 32.4%-49.4%) ranging from 32.4% to 49.4%. There was a significant heterogeneity among the studies (χ2 =21.02; p <0.001; I2 = 86.07%). The funnel plot for publication bias showed no evidence of asymmetry. Based on the results of Begg's and Egger's test no significant publication bias was observed. The study demonstrated a relative prevalence of P. aeruginosa among CF patients in Iran. Due to the rapid spread and infection severity of P. aeruginosa and other opportunistic pathogens, efforts are required to identify risk factors, reservoirs, transmission routes and source of infection. |
