The Immune System and Pathogenesis of Melanoma and Non-melanoma Skin Cancer.

Autor:	Schrom KP; Department of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA. kory.schrom@uhhospitals.org., Kim I; Department of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.; Department of Dermatology, Case Western Reserve University, Cleveland, OH, USA., Baron ED; Department of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.; Department of Dermatology, Case Western Reserve University, Cleveland, OH, USA.; Department of Dermatology, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, USA.
Jazyk:	angličtina
Zdroj:	Advances in experimental medicine and biology [Adv Exp Med Biol] 2020; Vol. 1268, pp. 211-226.
DOI:	10.1007/978-3-030-46227-7_11
Abstrakt:	Tumor development is the result of genetic derangement and the inability to prevent unfettered proliferation. Genetic derangements leading to tumorigenesis are variable, but the immune system plays a critical role in tumor development, prevention, and production. In this chapter, we will discuss the importance of the immune system as it relates to the development of skin cancer-both melanoma and non-melanoma skin cancers (NMSC).
Databáze:	MEDLINE
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