Preclinical to clinical translation of cenerimod, a novel S1P 1 receptor modulator, in systemic lupus erythematosus.

Autor: Strasser DS; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Froidevaux S; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Sippel V; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Gerossier E; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Grieder U; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Pierlot GM; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Kieninger-Graefitsch A; Inselspital Bern Universitätsklinik Für Kardiologie, Bern, Switzerland., Vezzali E; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Stalder AK; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Renault B; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Ryge J; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Hart A; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Mentzel U; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Groenen PMA; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Keller MP; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Trendelenburg M; Clinical Immunology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.; Division of Internal Medicine, University Hospital Basel, Basel, Switzerland., Martinic MM; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Murphy MJ; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland mark.murphy@idorsia.com.
Jazyk: angličtina
Zdroj: RMD open [RMD Open] 2020 Sep; Vol. 6 (2).
DOI: 10.1136/rmdopen-2020-001261
Abstrakt: Competing Interests: Competing interests: DSS, SF, VS, EG, UG, GP, EV, AKS, BR, JR, AH, UM, PMAG, MPK, MMM, and MJM are employees of Idorsia Pharmaceuticals Ltd. MT, grant research support.
Databáze: MEDLINE