Quantitative perfusion parameters of benign inflammatory breast pathologies: A descriptive study.

Autor: Ucar EA; Bor Public Hospital, Clinic of Radiology, Nigde, Turkey; University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Clinic of Radiology, Ankara, Turkey. Electronic address: elifayseucar@gmail.com., Durur-Subasi I; University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Clinic of Radiology, Ankara, Turkey; Istanbul Medipol University, Faculty of Medicine, Department of Radiology, Istanbul, Turkey., Yilmaz KB; University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Clinic of General Surgery, Ankara, Turkey., Arikok AT; University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Clinic of Pathology, Ankara, Turkey., Hekimoglu B; University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Clinic of Radiology, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Clinical imaging [Clin Imaging] 2020 Dec; Vol. 68, pp. 249-256. Date of Electronic Publication: 2020 Aug 27.
DOI: 10.1016/j.clinimag.2020.08.024
Abstrakt: Purpose: With this study, we evaluated the perfusion magnetic resonance imaging (MRI) features of benign inflammatory breast lesions for the first time and compared their K trans, K ep , V e values and contrast kinetic curves to benign masses and invasive ductal carcinoma (IDC).
Materials and Methods: Perfusion MRIs of the benign masses (n = 42), inflammatory lesions (n = 25), and IDCs (n = 16) were evaluated retrospectively in terms of K trans, K ep , V e values and contrast kinetic curves and compared by the Kruskal-Wallis, Mann-Whitney U, chi-square tests statistically. Cronbach α test was used to measure intraobserver and interobserver reliability.
Results: Mean K trans values were 0.052 for benign masses, 0.086 for inflammatory lesions and 0.101 for IDC (p < 0.001). Mean K ep values were 0.241 for benign masses, 0.435 for inflammatory lesions and 0.530 for IDC (p < 0.001). Mean V e values were 0.476 for benign masses, 0.318 for inflammatory lesions and 0.310 for IDC (p = 0.067). For inflammatory and IDC lesions, K trans and K ep values were found to be higher and V e values were lower than benign masses (p = 0.001 for K trans , p = 0.001 for K ep , p = 0.045 for V e ). There were excellent or good intra-interobserver reliabilities. For the kinetic curve pattern, most of the benign lesions showed progressive (81%), inflammatory lesions progressive (64%) and IDC lesions plateau (75%) patterns (p < 0.001).
Conclusions: On T1 perfusion MRI, similar to IDC lesions, inflammatory lesions demonstrate higher K trans and K ep and lower V e values than benign masses. Quantitative perfusion parameters are not helpful in differentiating them from IDC lesions.
(Copyright © 2020 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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