Neuropsychiatric manifestations in adult-onset Still's disease.

Autor:	Young G; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA., Tolla AS; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA tollaaza@msu.edu.; Hauenstein Neurosciences, Mercy Health Saint Mary's, Grand Rapids, Michigan, USA., Grinenko O; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA.; Hauenstein Neurosciences, Mercy Health Saint Mary's, Grand Rapids, Michigan, USA., Karanec K; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA.; Hauenstein Neurosciences, Mercy Health Saint Mary's, Grand Rapids, Michigan, USA.
Jazyk:	angličtina
Zdroj:	BMJ case reports [BMJ Case Rep] 2020 Sep 08; Vol. 13 (9). Date of Electronic Publication: 2020 Sep 08.
DOI:	10.1136/bcr-2020-235956
Abstrakt:	Adult-onset Still's disease (AOSD) is an uncommon inflammatory condition characterised by a triad of fevers, arthralgias and a salmon-coloured rash. It is also strongly associated with high ferritin levels, whose role in its pathogenesis is not entirely clear. Central nervous system (CNS) manifestations are exceedingly rare in this disease, accounting for only a handful of reported cases. Herein, we describe a case of a 63-year-old woman who developed new-onset psychiatric symptoms in the months preceding her diagnosis. 2 months after her diagnosis, she experienced an exacerbation of psychiatric symptoms followed by new-onset seizures in conjunction with an acute lung infection. In addition, we discuss two other previously reported cases of AOSD patients with psychiatric symptoms as their initial presentation. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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