| Autor: |
Oliveira CM; Graduate Program in Nutrition, Foods and Metabolism, Federal University of Mato Grosso, Cuiabá, MT 78060-900, Brazil., Ghezzi AC; Department of Pharmacology, State University of Campinas, Campinas, SP 13083-887, Brazil., Cambri LT; Graduate Program in Nutrition, Foods and Metabolism, Federal University of Mato Grosso, Cuiabá, MT 78060-900, Brazil.; Graduate Program in Physical Education, Federal University of Mato Grosso, Cuiabá, MT 78060-900, Brazil. |
| Jazyk: |
angličtina |
| Zdroj: |
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme [Appl Physiol Nutr Metab] 2021 Mar; Vol. 46 (3), pp. 221-228. Date of Electronic Publication: 2020 Sep 08. |
| DOI: |
10.1139/apnm-2020-0473 |
| Abstrakt: |
This study aimed to assess whether the blood glucose levels influence cardiac autonomic modulation under fasting and after carbohydrate overload conditions. Participants ( n = 108) were separated into lower blood glucose and higher blood glucose groups, based on the median (90.5 mg·dL -1 ) of fasting glucose assessed. The SD2, SDNN, LF indices, and LF/HF increased, and HF decreased after dextrose overload compared with fasting ( p < 0.05). Body mass (78.9 vs 69.7 kg), abdominal circumference (90.2 vs 82.2 cm), systolic (113 vs 108 mm Hg) and diastolic (72 vs 67 mm Hg) blood pressure were higher ( p < 0.05) in the higher blood glucose group. Heart rate variability (HRV) indices (SD1: 21.0 vs 26.5; SD2: 76.8: vs 86.1; RMSSD: 28.7 vs 37.5; SDNN: 56.1 vs 62.5 ms; pNN50: 10.6 vs 18.9%, HF: 328.4 vs 506.0; LF: 982.8 vs 1259.0 ms 2 ), and the area under the curve of these indices after dextrose overload were lower in the higher blood glucose group ( p < 0.05). Additionally, glycemia after dextrose overload was correlated with HRV indices (ρ = -0.216 to -0.273, p < 0.05). Individuals with higher blood glucose, even in the normality range, showed impairment in the cardiac autonomic modulation both at fasting and after carbohydrate overload. Novelty: Higher fasting blood glucose impairs cardiac autonomic modulation. Carbohydrate overload impairs cardiac autonomic modulation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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