Design and manufacture of a coronary stent INC-1 and initial tests in experimental animal model.

Autor:	Abundes-Velasco A; Subdirectorate for Innovation and Development Projects, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico., Jiménez-Rodríguez GM; Department of Hemodynamics, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico., Romero-Ibarra JL; Department of Interventional Cardiology, Hospital Star Médica Querétaro, Querétaro, Mexico., Sandoval-Jones JP; Department of Hemodynamics, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico., Sánchez-Pérez E; Subdirectorate for Innovation and Development Projects, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico., Galaz-Méndez R; General Directorate and Department of Biomedical Engineering, GSE Biomedical, Hermosillo, Sonora, Mexico., Ulacia-Flores P; General Directorate and Department of Biomedical Engineering, GSE Biomedical, Hermosillo, Sonora, Mexico., Farjat-Pasos JI; Department of Hemodynamics, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico., Padilla-Ibarra J; Department of Hemodynamics, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico., González SA; Subdirectorate for Innovation and Development Projects, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico., Martínez-Ríos MA; Department of Hemodynamics, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico., Peña-Duque MA; Subdirectorate for Innovation and Development Projects, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico., Rodriguez-Parra DA; Subdirectorate for Innovation and Development Projects, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Jazyk:	angličtina
Zdroj:	Archivos de cardiologia de Mexico [Arch Cardiol Mex] 2020; Vol. 90 (2), pp. 142-147.
DOI:	10.24875/ACME.M20000108
Abstrakt:	In this paper, we describe our coronary stent (INC-1) design and development, the way that we found the specific characteristics needed for our device including biophysics aspects, design, finite element testing, manufacturing, and mechanic trials, we submitted and animal models experiences. The stent platform was cobalt-chromium L605 (Co-Cr), with struts thickness of 80 μm, balloon expandable. We placed the coronary stent INC-1 on a rabbit and dog models so we can evaluate efficacy and security of the device in relationship to its biomechanical properties including navigation capacity, traceability, symmetric expansion, and safety, as well as endothelial attachment, thrombogenicity, and lack of involvement of secondary branches in these models. We succeeded in efficacy and safety of the device after fluoroscopy-guided implant proving excellent capacity of release system, traceability, fluoroscopic visualization, symmetric expansion, and complete endothelial attach. Furthermore, we obtained a good post-implant balloon withdrawal, functional integrity, and no vascular complications. We observed adequate clinical evolution 3 weeks after the stent implantation. (Copyright: © 2020 Permanyer.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu