| Autor: |
Siqueira IR; Universidade Federal do Rio Grande do Sul., Basso CG; Universidade Federal do Rio Grande do Sul., Pizzolato LS; Universidade Federal do Rio Grande do Sul., Cechinel LR; Universidade Federal do Rio Grande do Sul., Bertoldi K; Universidade Federal do Rio Grande do Sul., Dalpiaz M; Centro Universitário Metodista IPA., de Souza MP; Centro Universitário Metodista IPA., Elsner VR; Centro Universitário Metodista IPA. |
| Jazyk: |
angličtina |
| Zdroj: |
Research quarterly for exercise and sport [Res Q Exerc Sport] 2022 Mar; Vol. 93 (1), pp. 77-86. Date of Electronic Publication: 2020 Sep 08. |
| DOI: |
10.1080/02701367.2020.1798332 |
| Abstrakt: |
Purpose : Our goals were to evaluate the effect of a 10-km running trial on inflammatory and epigenetic markers of 10-km runners and correlate the biochemical findings with anthropometric variables and performance. Methods : Twenty trained 10-km runners and seven sedentary male volunteers were recruited. Venous blood samples were collected at different times: under resting conditions, before the 10 Km race, and immediately after the finish. Inflammatory markers (IL-6, IL-10, and IL-β) and cortisol levels were evaluated in plasma, while DNA methyltransferases (DNMT1 and DNMT3b) contents were measured in peripheral blood mononuclear cells (PBMCs). Results : Higher levels of plasma IL-6 levels were observed in 10-km runners compared to the sedentary group. After the trial, the runners had a significant increase on IL-6, IL-10, and cortisol plasma levels compared to baseline. Conclusion : Our findings suggest that inflammatory profile, but not DNMT content, influences aerobic performance in 10-km runners. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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