Pixel CO 2 Laser for the Treatment of Stress Urinary Incontinence: A Prospective Observational Multicenter Study.

Autor: Franić D; Faculty of Medicine, University of Maribor, Maribor, Slovenia.; Outpatient Clinic Ob&Gyn, Slatina, Slovenia., Fistonić I; Clinic Ob/Gyn, Zagreb, Croatia.; Medical School University of Rijeka, Croatia., Franić-Ivanišević M; Health Center Slovenske Konjice, OB&Gyn Unit, Slovenske Konjice, Slovenia., Perdija Ž; CIIM Plus, Medical Center, Maribor, Slovenia., Križmarić M; Faculty of Medicine, University of Maribor, Maribor, Slovenia.; Faculty of Health Sciences, University of Maribor, Maribor, Slovenia.
Jazyk: angličtina
Zdroj: Lasers in surgery and medicine [Lasers Surg Med] 2021 Apr; Vol. 53 (4), pp. 514-520. Date of Electronic Publication: 2020 Sep 08.
DOI: 10.1002/lsm.23319
Abstrakt: Background and Objectives: Energy-based treatments have been found to be a promising treatment modality for improving stress urinary incontinence (SUI) symptoms. This prospective two-center study was designed to evaluate the efficacy of fractional-pixel CO 2 laser for the treatment of SUI.
Study Design/materials and Methods: Eighty-five women with SUI symptoms as per the cough stress test and validated International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI-SF), were treated intravaginally with Pixel-CO 2 laser. Two treatment sessions were performed with a 1-month interval. Safety and treatment tolerance were assessed by the visual analog scale (VAS) immediately and at 1 week after each laser treatment. Associations of age and body mass index (BMI) with the ICIQ-UI-SF score were statistically assessed by the Jonckheere-Terpstra test.
Results: The ICIQ-UI-SF score was 12.0 at baseline, 7.0, after the first treatment, and 3.5 after the second treatment (P = 0.001). For women with BMI (25.0-29.9), the ICIQ-UI-SF score was 9.0 at the baseline, 6.0 after 1 month, and 5.0 at the 6 months follow-up visit (P = 0.04). For women with BMI ≥ 30.0, the ICIQ-UI-SF score was reduced from 14.0 to 8.0 1 month after the baseline and 5.0 at the 6-month follow-up visit (P = 0.001). SUI severity evaluation at baseline showed that 27.1% of women had mild, 24.7% had moderate, 45.9% had severe, and 2.4% had very severe SUI symptoms. SUI severity scores were significantly reduced, with 45.8% of women with no SUI symptoms, 18.8% with mild, 20.8% with moderate, and 14.6% with severe SUI symptoms at the 6-month follow-up. The patient's evaluation of VAS after the first treatment was 1.0-1.5 (0-10) and 0.0 1 week after the second treatment.
Conclusion: Fractional-pixel CO 2 laser is safe and effective for treating SUI. No adverse event or significant pain was reported during or after the procedure. Its safety and efficacy are clearly demonstrated. Lasers Surg. Med. © 2020 Wiley Periodicals LLC.
(© 2020 Wiley Periodicals LLC.)
Databáze: MEDLINE
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