Local and systemic immune mediators of Morada Nova lambs with divergent Haemonchus contortus resistance phenotypes.
Autor: | Barbosa Toscano JH; Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (UNESP), Jaboticabal, Brazil., Okino CH; Embrapa Pecuária Sudeste, São Carlos, Brazil., Barbosa Dos Santos I; Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (UNESP), Jaboticabal, Brazil., Giraldelo LA; Centro Universitário Central Paulista, São Carlos, Brazil., Borsch von Haehling M; Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (UNESP), Jaboticabal, Brazil., Novita Esteves S; Embrapa Pecuária Sudeste, São Carlos, Brazil., Bassetto CC; Instituto de Biociências, Universidade Estadual Paulista (UNESP), Botucatu, Brazil., Talamini do Amarante AF; Instituto de Biociências, Universidade Estadual Paulista (UNESP), Botucatu, Brazil., de Souza Chagas AC; Embrapa Pecuária Sudeste, São Carlos, Brazil. |
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Jazyk: | angličtina |
Zdroj: | Parasite immunology [Parasite Immunol] 2020 Dec; Vol. 42 (12), pp. e12790. Date of Electronic Publication: 2020 Sep 18. |
DOI: | 10.1111/pim.12790 |
Abstrakt: | Aims: Local and systemic immune mediators of Morada Nova lambs with divergent Haemonchus contortus resistance phenotypes were evaluated. Methods and Results: Lambs were ranked through faecal egg counts (FEC) after two parasitic challenges with 4,000 H.contortus L Conclusion: These data indicate that resistant lambs had an immune response mediated by antibody-mediated cytotoxicity. Also, the systemic humoral profile, particularly IgA isotype, seems to be a good resistance marker for Morada Nova sheep, as we found differences between groups even when FEC did not differ. (© 2020 John Wiley & Sons Ltd.) |
Databáze: | MEDLINE |
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