Recommendations for Pregnancy in Rare Inherited Anemias.
Autor: | Taher AT; Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon., Iolascon A; Department of Molecular Medicine and Medical Biotechnologies, University Federico II of Naples, Italy.; CEINGE Advanced Biotechnologies, Naples, Italy., Matar CF; Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon., Bou-Fakhredin R; Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon., de Franceschi L; Department of Medicine, Section of Internal Medicine, University of Verona, Policlinico GB Rossi, AOUI, Verona, Italy., Cappellini MD; Department of Clinical Sciences and Community, University of Milan, IRCCS Ca' Granda Foundation Maggiore Policlinico Hospital, Milan, Italy., Barcellini W; Hematology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Russo R; Department of Molecular Medicine and Medical Biotechnologies, University Federico II of Naples, Italy.; CEINGE Advanced Biotechnologies, Naples, Italy., Andolfo I; Department of Molecular Medicine and Medical Biotechnologies, University Federico II of Naples, Italy.; CEINGE Advanced Biotechnologies, Naples, Italy., Tyan P; Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Gulbis B; Departments of Clinical Chemistry and Molecular Genetics, Academic Hospital Erasme, Free University of Brussels, Brussels, Belgium., Aydinok Y; Department of Pediatric Hematology and Oncology, Ege University Hospital, Izmir, Turkey., Anagnou NP; Cell and Gene Therapy Laboratory, Centre of Basic Research II, Biomedical Research Foundation of The Academy of Athens (BRFAA), Athens, Greece., Bencaiova GA; Department of Obstetrics and Antenatal Care, University Hospital Basel, Basel, Switzerland., Tamary H; Department of Pediatric Hematology-Oncology, Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Martinez PA; Department of biological hematology, CHU de Montpellier, and Montpellier University, Montpellier, France., Forni G; Centro della Microcitemia e delle Anemie Congenite, Ospedale Galliera, Genova, Italy., Vindigni R; United Onlus - Federazione Italiana delle Thalassemie, Emoglobinopatie Rare e Drepanocitosi, Ferrara, Italy. |
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Jazyk: | angličtina |
Zdroj: | HemaSphere [Hemasphere] 2020 Aug 12; Vol. 4 (4), pp. e446. Date of Electronic Publication: 2020 Aug 12 (Print Publication: 2020). |
DOI: | 10.1097/HS9.0000000000000446 |
Abstrakt: | Rare inherited anemias are a subset of anemias caused by a genetic defect along one of the several stages of erythropoiesis or in different cellular components that affect red blood cell integrity, and thus its lifespan. Due to their low prevalence, several complications on growth and development, and multi-organ system damage are not yet well defined. Moreover, during the last decade there has been a lack of proper understanding of the impact of rare anemias on maternal and fetal outcomes. In addition, there are no clear-cut guidelines outlining the pathophysiological trends and management options unique to this special population. Here, we present on behalf of the European Hematology Association, evidence- and consensus-based guidelines, established by an international group of experts in different fields, including hematologists, gynecologists, general practitioners, medical geneticists, and experts in rare inherited anemias from various European countries for standardized and appropriate choice of therapeutic interventions for the management of pregnancy in rare inherited anemias, including Diamond-Blackfan Anemia, Congenital Dyserythropoietic Anemias, Thalassemia, Sickle Cell Disease, Enzyme deficiency and Red cell membrane disorders. Competing Interests: The authors have no conflicts of interest to disclose. (Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the European Hematology Association.) |
Databáze: | MEDLINE |
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