Lung Adenocarcinoma during Pregnancy: 11-Year Follow-Up.

Autor: Acosta Rojas A; Department of Radiation Oncology, Hospital Universitario Madrid Sanchinarro-CIOCC, Madrid, Spain., Collazo-Lorduy A; Department of Medical Oncology, Hospital Universitario Madrid Sanchinarro-CIOCC, Madrid, Spain., Remon J; Department of Medical Oncology, CIOCC-Barcelona Hospital HM Delfos, Barcelona, Spain., Hernando Requejo O; Department of Radiation Oncology, Hospital Universitario Madrid Sanchinarro-CIOCC, Madrid, Spain., Jiménez-Munarriz B; Department of Medical Oncology, Hospital Universitario Madrid Sanchinarro-CIOCC, Madrid, Spain., Rubio Rodríguez MC; Department of Radiation Oncology, Hospital Universitario Madrid Sanchinarro-CIOCC, Madrid, Spain., De Castro J; Department of Medical Oncology, Hospital Universitario Madrid Sanchinarro-CIOCC, Madrid, Spain.
Jazyk: angličtina
Zdroj: Case reports in oncology [Case Rep Oncol] 2020 Jul 29; Vol. 13 (2), pp. 892-895. Date of Electronic Publication: 2020 Jul 29 (Print Publication: 2020).
DOI: 10.1159/000508360
Abstrakt: The incidence of lung cancer during pregnancy is rising due to the high rate of smokers in young women and the late mean age of pregnancy; in addition, considering that the patients are young women with a higher incidence of molecular alterations, molecular testing in lung adenocarcinoma should always be performed, even in pregnancy. Here, we report the case of a lung adenocarcinoma diagnosed during pregnancy with a long survival who benefitted from brain radiotherapy, conventional chemotherapy, and ALK TKI-targeted treatment. It reveals the safety of whole brain radiotherapy during pregnancy and consideration of other brain radiation techniques even in palliative cases, which should be personalized and managed by a multidisciplinary team. However, upfront management of brain metastasis in ALK-positive patients remains unresolved.
Competing Interests: The authors declare no conflicts of interest.
(Copyright © 2020 by S. Karger AG, Basel.)
Databáze: MEDLINE
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