Granuloma Annulare, a Possible Paradoxical Reaction of the Adalimumab Treatment in a Severe Case of Psoriasis Vulgaris.
Autor: | MĂrculescu F; University of Medicine and Pharmacy of Craiova, Romania., PĂtraȘcu V; University of Medicine and Pharmacy of Craiova, Romania., Tutunaru CV; University of Medicine and Pharmacy of Craiova, Romania., Ochiana L; University of Medicine and Pharmacy of Craiova, Romania. |
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Jazyk: | angličtina |
Zdroj: | Current health sciences journal [Curr Health Sci J] 2020 Apr-Jun; Vol. 46 (2), pp. 203-206. Date of Electronic Publication: 2020 Jun 30. |
DOI: | 10.12865/CHSJ.46.02.16 |
Abstrakt: | Granuloma annulare (GA) is a benign chronic inflammatory dermatosis, self-limited, slightly pruritic or asymptomatic in the majority of the cases, with specific clinically and histologically features, that occurs in all age groups, but it is rare in infancy. GA is associated to five clinical variants: localized, generalized, perforating, subcutaneous and arcuate dermal erythema. The etiology of GA is usually unknown, but in 60-75% of the cases it is associated with metabolic disorders (diabetes mellitus, dyslipidemia), thyroid disorders, neoplasms, infections or drug induced. We present a psoriasis case treated with anti TNFα agents, Adalimumab, that after three and a half years of treatment developed GA. (Copyright © 2014, Medical University Publishing House Craiova.) |
Databáze: | MEDLINE |
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