Brunner's glands hamartoma with pylorus obstruction: a case report and review of literature.

Autor: Bakir MA; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., AlYousef MY; College of Medicine, King Saud University, Riyadh, Saudi Arabia., Alsohaibani FI; Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Alsaad KO; Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Jazyk: angličtina
Zdroj: Journal of surgical case reports [J Surg Case Rep] 2020 Aug 26; Vol. 2020 (8), pp. rjaa191. Date of Electronic Publication: 2020 Aug 26 (Print Publication: 2020).
DOI: 10.1093/jscr/rjaa191
Abstrakt: Proliferative lesions of the Brunner's glands are uncommonly encountered lesions of the small intestine, originating from the deeply seated mucosal and submucosal Brunner's glands, mainly in the duodenum. The vast majorities of these lesions are benign and include Brunner's glands hyperplasia (adenomas/nodules) and hamartomas. The etiology and pathogenesis of these lesions are not fully understood, and the diagnosis can sometimes be challenging. We report a case of Brunner's gland hamartoma in a 57-year-old man who presented with chronic dyspepsia, hematemesis and weight loss. Endoscopic and radiological investigations show a submucosal polypoid lesion at the first part of the duodenum. Routine endoscopic biopsies demonstrated normal duodenal mucosa. The lesion considered endoscopically unresectable and was surgically resected. Frozen section examination and intraoperative consultation showed unremarkable duodenal mucosa and histologically bland Brunner's glands.
(Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.)
Databáze: MEDLINE
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