A Pilot Validation Study of the Newborn Behavioral Observations System: Associations with Salivary Cortisol and Temperament.

Autor:	Congdon JL; Division of General Pediatrics, Department of Pediatrics, University of California San Francisco, San Francisco, CA., Nugent JK; Division of Developmental Medicine, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA., McManus BM; Department of Health Systems, Management, and Policy, University of Colorado, Denver, Colorado., Coccia M; Division of Developmental Medicine, Department of Psychiatry, University of California San Francisco, San Francisco, California., Bush NR; Division of Developmental Medicine, Department of Psychiatry and Department of Pediatrics, University of California San Francisco, San Francisco, California.
Jazyk:	angličtina
Zdroj:	Journal of developmental and behavioral pediatrics : JDBP [J Dev Behav Pediatr] 2020 Dec; Vol. 41 (9), pp. 716-723.
DOI:	10.1097/DBP.0000000000000842
Abstrakt:	Objective: There are few standardized neonatal neurobehavioral instruments available for longitudinal child development research. We adapted an established clinical tool, the Newborn Behavioral Observations (NBO) system, for research by standardizing the administration protocol and expanding the 3-point coding scale to 5 points. Methods: We administered the 5-point NBO to 144 racially/ethnically diverse late preterm or term infants born to low-income women (average age 5 weeks). Cronbach's alphas were calculated to determine internal consistency reliability of Autonomic, Motor, Organization of State, and Responsivity subscales. We examined concurrent validity using subscale associations with infant salivary cortisol reactivity to the NBO and maternally reported infant temperament. Results: Two of the 4 NBO subscales, Organization of State and Responsivity, had excellent (0.91) and good (0.76) reliability, respectively, and were retained for further analyses. Infants with higher Organization of State scores (more optimal regulation) demonstrated lower cortisol reactivity (r = -0.30, p < 0.01) and temperamental negativity (r = -0.16, p < 0.05). Responsivity was unrelated to cortisol reactivity or temperament. Conclusions: State regulation, as measured by the 5-point NBO, was associated with a biologic marker of infant stress response to the NBO administration and reported temperament. Poor reliability of the NBO's 3-item Autonomic and 7-item Motor subscales suggests that further psychometric research in other samples and likely refinement are needed. Given the paucity of neurobehavioral assessment tools for infants, these findings justify such research as next steps in the incremental progression toward the development of a practical, reliable, and predictive measure of early neurobehavioral development.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu