Circadian Disruption in Critical Illness.

Autor:	Jobanputra AM; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States., Scharf MT; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States.; Department of Neurology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States., Androulakis IP; Biomedical Engineering Department, Rutgers University, Piscataway, NJ, United States.; Chemical and Biochemical Engineering Department, Rutgers University, Piscataway, NJ, United States.; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States., Sunderram J; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States.
Jazyk:	angličtina
Zdroj:	Frontiers in neurology [Front Neurol] 2020 Aug 11; Vol. 11, pp. 820. Date of Electronic Publication: 2020 Aug 11 (Print Publication: 2020).
DOI:	10.3389/fneur.2020.00820
Abstrakt:	Circadian rhythms play a vital role in metabolic, hormonal, and immunologic function and are often disrupted in patients in the ICU. Circadian rhythms modulate the molecular machinery that responds to injury and illness which can impact recovery. Potential factors contributing to the alteration in circadian rhythmicity in intensive care unit (ICU) patients include abnormal lighting, noise, altered feeding schedules, extensive patient care interactions and medications. These alterations in circadian rhythms in ICU patients may affect outcomes and therefore, normalization of circadian rhythmicity in critically ill patients may be an important part of ICU care. (Copyright © 2020 Jobanputra, Scharf, Androulakis and Sunderram.)
Databáze:	MEDLINE
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