An evaluation of electrocoagulation and thermal diffusion following radiofrequency microneedling using an in vivo porcine skin model.
Autor: | Wootten S; Department of Research and Development, Aesthetics Biomedical Inc., Phoenix, AZ, USA., Zawacki ZE; Department of Research Services, Comparative Biosciences Inc., Sunnyvale, CA, USA., Rheins L; Department of Research and Development, Aesthetics Biomedical Inc., Phoenix, AZ, USA., Meschter C; Department of Research Services, Comparative Biosciences Inc., Sunnyvale, CA, USA., Draelos ZD; Dermatology Consulting Services, PLLC, High Point, NC, USA. |
---|---|
Jazyk: | angličtina |
Zdroj: | Journal of cosmetic dermatology [J Cosmet Dermatol] 2021 Apr; Vol. 20 (4), pp. 1133-1139. Date of Electronic Publication: 2020 Sep 07. |
DOI: | 10.1111/jocd.13690 |
Abstrakt: | Background: Few studies exist that examined the role of radiofrequency microneedling (RFMN) in skin electrocoagulation. This research utilized a porcine model to understand bipolar dermal delivery from an RFMN device. Aims: The objective of this study was to elucidate and compare the dermal thermal effects of a RFMN device producing 1 and 2 MHz signal amplitudes, with respective voltage and current gradients, utilizing noninsulated and insulated needles by examining the histologic effects on porcine skin. Methods: Two separate animal studies were conducted to evaluate the electrocoagulation and thermal diffusion effects using the RFMN device. The electrocoagulation effects were assessed histologically using hematoxylin and eosin (H&E) staining, and heating effects were assessed through thermal imaging. Results: Histology results of the thermal injury induced by insulated needles demonstrated that 2 MHz resulted in a narrow and concentrated coagulation zone as compared to 1 MHz. Further, the 1 MHz insulated needle resulted in ovular shaped tissue coagulation as compared to 2 MHz tissue coagulation that was columnar. Finally, full thermal diffusion occurs seconds after the set RF conduction time. Conclusion: The findings showed that 1 MHz insulated needle produces larger coagulations with an increase in power level, the 1 MHz noninsulated array was comparable to the 2 MHz insulated array with similar histologic features, and heat dissipates seconds after the set conduction time. (© 2020 Aesthetics Biomedical, Inc. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.) |
Databáze: | MEDLINE |
Externí odkaz: |