| Autor: |
Burroughs Peña MS; Stanford Health Care Oakland CA., Uwamungu JC; Department of Medicine Albert Einstein College of Medicine Bronx NY., Bulka CM; Department of Environmental Sciences and Engineering University of North Carolina Chapel Hill NC., Swett K; Department of Medicine Albert Einstein College of Medicine Bronx NY.; Department Epidemiology and Population Health Albert Einstein College of Medicine Bronx NY., Perreira KM; Department of Social Medicine University of North Carolina School of Medicine Chapel Hill NC., Kansal MM; Institute for Minority Health Research University of Illinois Chicago IL., Loop MS; Department of Biostatistics University of North Carolina Gillings School of Global Public Health Chapel Hill NC., Hurwitz BE; Behavioral Medicine Research Center, Miller School of Medicine University of Miami FL.; Department of Psychology University of Miami Coral Gables FL., Daviglus M; Institute for Minority Health Research University of Illinois Chicago IL., Rodriguez CJ; Department of Medicine Albert Einstein College of Medicine Bronx NY.; Department Epidemiology and Population Health Albert Einstein College of Medicine Bronx NY. |
| Abstrakt: |
Background Our objective was to determine associations of occupational exposures with cardiac structure and function in Hispanic/Latino adults. Methods and Results Employed participants were included (n=782; 52% women, mean age 52.9 years). Occupational exposures to burning wood, vehicle exhaust, solvents, pesticides, and metals at the current and longest-held job were assessed by questionnaire. Survey multivariable linear regression analyses were used to model the relationship of each self-reported exposure with echocardiographic measures of cardiac structure and function. Exposure to burning wood at the current job was associated with decreased left ventricular (LV) ejection fraction (-3.1%; standard error [SE], 1.0 [ P =0.002]). When the analysis was restricted to exposure at the longest-held job, occupational exposure to burning wood was associated with increased LV diastolic volume (6.7 mL; SE, 1.6 [ P <0.0001]), decreased LV ejection fraction (-2.7%; SE, 0.6 [ P <0.0001]), worse LV global longitudinal strain (1.0%; SE, 0.3 [ P =0.0009]), and decreased right ventricular fractional area change (-0.02; SE, 0.004 [ P <0.001]). Exposure to pesticides was associated with worse average global longitudinal strain (0.8%; SE, 0.2 [ P <0.0001]). Exposure to metals was associated with worse global longitudinal strain in the 2-chamber view (1.0%; SE, 0.5 [ P =0.04]), increased stroke volume (3.6 mL; SE, 1.6 [ P =0.03]), and increased LV mass indexed to BSA (9.2 g/m 2 ; SE, 3.8 [ P =0.01]) or height (4.4 g/m 2.7 ; SE, 1.9 [ P =0.02]). Conclusions Occupational exposures to burning wood, vehicle exhaust, pesticides, and metals were associated with abnormal parameters of LV and right ventricular systolic function. Reducing exposures to toxic chemicals and particulates in the workplace is a potential opportunity to prevent cardiovascular disease in populations at risk. |
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