Ophthalmological findings in patients with leukaemia in a Colombian population.

Autor: Rangel CM; Retina y Vítreo, Fundación Oftalmológica de Santander-Clínica Carlos Ardila Lülle (FOSCAL), Floridablanca, Colombia., Ortiz Á; Neurooftalmología, Fundación Oftalmológica de Santander-Clínica Carlos Ardila Lülle (FOSCAL), Floridablanca, Colombia., Sánchez-Ávila R; Oftalmología, Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de Oviedo, Oviedo, España., Varón C; Retina y Vítreo, Fundación Oftalmológica de Santander-Clínica Carlos Ardila Lülle (FOSCAL), Floridablanca, Colombia., Cárdenas PL; Neurooftalmología, Fundación Oftalmológica de Santander-Clínica Carlos Ardila Lülle (FOSCAL), Floridablanca, Colombia., Escaf LC; Oftalmología, Fundación Oftalmológica de Santander-Clínica Carlos Ardila Lülle (FOSCAL), Floridablanca, Colombia. Electronic address: Lescaf@gmail.com., Jaramillo D; Oftalmología, Fundación Oftalmológica de Santander-Clínica Carlos Ardila Lülle (FOSCAL), Floridablanca, Colombia., Rodriguez H; Oftalmología, Fundación Oftalmológica de Santander-Clínica Carlos Ardila Lülle (FOSCAL), Floridablanca, Colombia.
Jazyk: English; Spanish; Castilian
Zdroj: Archivos de la Sociedad Espanola de Oftalmologia [Arch Soc Esp Oftalmol (Engl Ed)] 2021 May; Vol. 96 (5), pp. 242-250. Date of Electronic Publication: 2020 Aug 20.
DOI: 10.1016/j.oftal.2020.05.021
Abstrakt: Objective: To report the ocular manifestations in patients with leukaemia.
Methods: This is a retrospective, descriptive and observational study in patients with ocular manifestations of leukaemia.
Results: A total of 14 eyes were evaluated corresponding to 8 patients (5 women and 3 men) with ocular manifestations of leukaemia. The mean age at diagnosis was 43 years (31-76 years). Six eyes corresponded to patients with acute myeloid leukaemia (AML), four eyes to acute lymphoid leukaemia (ALL), two eyes to chronic myeloid leukaemia (CML), and the remaining two belonged to patients with hairy cell leukaemia (HCL). The primary ocular findings were choroidal invasion in 12 eyes (85.7%), retinal infiltration in 4 eyes (28.6%), and neuro-ophthalmic disorders in 4 eyes (28.6%). The mean visual acuity improved from 0.689 to 0.449 (logMAR) (P=.012) after the systemic and intrathecal chemotherapy. Of the eight patients, four died from systemic complications of the underlying disease.
Conclusions: This is the first report of multiple ocular manifestations secondary to leukaemia in a Colombian population. It is important to keep in mind that this disease is included within the masquerade syndromes and that the ophthalmological findings that, while subtle, can also be devastating and be signs of a life-threatening disease.
(Copyright © 2020 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE
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