Fipronil and 2,4-D effects on tropical fish: Could avoidance response be explained by changes in swimming behavior and neurotransmission impairments?

Autor: Moreira RA; NEEA/CRHEA/SHS and PPG-SEA, São Carlos Engineering School, University of São Paulo, Av Trabalhador São Carlense, 400, 13.560-970, São Carlos, Brazil. Electronic address: raquel.moreira87@yahoo.com.br., Araújo CVM; Department of Ecology and Coastal Management, Institute of Marine Sciences of Andalusia (CSIC), Campus Universitario Río San Pedro, 11519, Puerto Real, Spain., Junio da Silva Pinto T; NEEA/CRHEA/SHS and PPG-SEA, São Carlos Engineering School, University of São Paulo, Av Trabalhador São Carlense, 400, 13.560-970, São Carlos, Brazil., Menezes da Silva LC; NEEA/CRHEA/SHS and PPG-SEA, São Carlos Engineering School, University of São Paulo, Av Trabalhador São Carlense, 400, 13.560-970, São Carlos, Brazil., Goulart BV; Analytical Chemistry Department, Institute of Chemistry, University of Campinas, Campinas, São Paulo, Brazil., Viana NP; Physiological Sciences Department, Federal University of São Carlos, Av. Washington Luiz Km 235, 13565-905, São Carlos, São Paulo, Brazil., Montagner CC; Analytical Chemistry Department, Institute of Chemistry, University of Campinas, Campinas, São Paulo, Brazil., Fernandes MN; Physiological Sciences Department, Federal University of São Carlos, Av. Washington Luiz Km 235, 13565-905, São Carlos, São Paulo, Brazil., Gaeta Espindola EL; NEEA/CRHEA/SHS and PPG-SEA, São Carlos Engineering School, University of São Paulo, Av Trabalhador São Carlense, 400, 13.560-970, São Carlos, Brazil.
Jazyk: angličtina
Zdroj: Chemosphere [Chemosphere] 2021 Jan; Vol. 263, pp. 127972. Date of Electronic Publication: 2020 Aug 14.
DOI: 10.1016/j.chemosphere.2020.127972
Abstrakt: Brazil is the largest producer of sugarcane, a crop largely dependent on chemical control for its maintenance. The insecticide fipronil and herbicide 2,4-D stand out among the most commonly used pesticides and, therefore, environmental consequences are a matter of concern. The present study aimed to investigate the toxicity mechanisms of Regent® 800 WG (a.i. fipronil) and DMA® 806 BR (a.i. 2,4-D) pesticides using forced and non-forced exposures through an integrative approach: firstly, to assess whether contamination by fipronil and 2,4-D can trigger the avoidance behavior of the fish Danio rerio (zebrafish) and Hyphessobrycon eques (serpae tetra or mato-grosso). Additionally, the effects on fish were analyzed considering the swimming behavior together with a biomarker of neurotoxicity, the activity of acetylcholinesterase (AChE). In avoidance tests with pesticide gradients, D. rerio avoided the highest concentrations of the two compounds and H. eques avoided only the highest concentration of 2,4-D. The swimming behavior (distance moved) was reduced and AChE was inhibited when D. rerio was exposed to fipronil. The 2,4-D affected the swimming (maximum speed) of H. eques, but AChE was not altered. Avoidance response seemed not to have been affected by possible effects of contaminants on swimming behavior and Ache activity. This study showed the importance of knowing the avoidance capacity, swimming behavior and neurotoxic effects of pesticides on fish in an integrated and realistic context of exposure in environments contaminated with pesticides and can be useful as ecologically relevant tools for ecological risk assessment.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: