Cardiovascular Risk Factors: It's Time to Focus on Variability!

Autor: Barnett MP; The Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY, USA., Bangalore S; The Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY, USA.
Jazyk: angličtina
Zdroj: Journal of lipid and atherosclerosis [J Lipid Atheroscler] 2020 May; Vol. 9 (2), pp. 255-267. Date of Electronic Publication: 2020 Apr 07.
DOI: 10.12997/jla.2020.9.2.255
Abstrakt: Atherosclerotic heart disease remains a leading cause of morbidity and mortality worldwide. While extensive research supports cardiovascular risk factor reduction in the form of achieving evidence-based blood pressure, lipid, glucose, and body weight targets as a means to improve cardiovascular outcomes, residual risk remains. Emerging data have demonstrated that the intraindividual variability of these risk factor targets potentially contribute to this residual risk. It may therefore be time to define risk factor by not only its magnitude and duration as done traditionally, but perhaps also by the variability of that particular risk factor over time.
Competing Interests: Conflict of Interest: Dr. Bangalore has been an ad hoc consultant/speaker for Abbott Vascular, Biotronik, Pfizer, Merck, The Medicines Company, and AstraZeneca; and has received research grants from Abbott Vascular and the National Heart, Lung, and Blood Institute.
(Copyright © 2020 The Korean Society of Lipid and Atherosclerosis.)
Databáze: MEDLINE