Eosinophilia
| Autor: | Kanuru S; Central Arkansas Veterans Healthcare System, Sapra A; Southern Illinois University School of Medicine |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | 2022 Jan. |
| Abstrakt: | Eosinophils are a kind of blood granulocytes that express cytoplasmic granules that contain basic proteins and bind with acidic dyes like “eosin.” They derive from bone marrow, and IL-5, IL-3, and GM-CSF stimulate their production.[1] They have a circulating half-life of 4.5 to 8 hours. They can reside in tissues, mostly in the respiratory tract, gastrointestinal tract, for 8 to 12 days. Eosinophils are less than 5% of circulating leucocytes. Eosinophilia is defined as an increase of circulating eosinophils >500 /mm^3.[1] Based on the counts, eosinophilia can subdivide into different categories: mild (500 and 1500/mm^3), moderate (150 to 5000/mm3), and severe (>5000/mm^3). Hypereosinophilic syndrome is defined as an absolute eosinophil count greater than 1500/mm3 on two occasions at least one month apart or marked tissue eosinophilia.[2] (Copyright © 2022, StatPearls Publishing LLC.) |
| Databáze: | MEDLINE |
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