Hypothalamic Hamartoma
| Autor: | Carballo Cuello CM; Section of Neurosurgery, University of Puerto Rico, De Jesus O; University of Puerto Rico, Medical Sciences Campus, Neurosurgery Section |
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| Jazyk: | angličtina |
| Zdroj: | 2022 Jan. |
| Abstrakt: | Hypothalamic hamartomas are congenital non-progressive lesions in the hypothalamus that occur during fetal development. Two anatomical subtypes are recognized depending on the location of the mass-like lesion. The first type is the intrahypothalamic lesion that connects with the posterior hypothalamus and third ventricle; they appear near the mamillary bodies and are usually associated with gelastic seizures.[1][2] The second type is the parahypothalamic or pedunculated lesion located near the anterior hypothalamus, tuber cinereum, or pituitary stalk and attaches only to the floor of the third ventricle. It is usually associated with signs of precocious puberty caused by increasing the release of gonadotropin-releasing hormone (GnRH).[2][3] These lesions typically develop a disabling course presenting with multiple seizure types, cognitive decline, and psychiatric symptoms.[4] (Copyright © 2022, StatPearls Publishing LLC.) |
| Databáze: | MEDLINE |
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