| Autor: |
Zargarbashi R; Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran., Panjavi B; Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran., Keshavarz-Fathi M; Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.; Cancer Immunology Project, Universal Scientific Education and Research Network, Tehran, Iran. |
| Jazyk: |
angličtina |
| Zdroj: |
The international journal of lower extremity wounds [Int J Low Extrem Wounds] 2023 Mar; Vol. 22 (1), pp. 113-116. Date of Electronic Publication: 2020 Aug 17. |
| DOI: |
10.1177/1534734620948768 |
| Abstrakt: |
Nicolau syndrome (NS) is a rare cutaneous drug reaction in response to injections administered via any route. Based on the available studies in the medical literature, NS presents as skin and subcutaneous fat necrosis, and typically, it does not cause severe complications such as acute limb ischemia or death. In this study, we report the case of a 6-year-old boy who received an intramuscular injection of benzathine penicillin G for the treatment of bacterial pharyngitis, and subsequently developed a severe case of NS, which eventually led to below-knee amputation of the right lower limb. Although a few approaches have been suggested for the management of NS, they might not be effective under certain circumstances. Early detection, close monitoring, and consistent interventions, such as surgical fasciotomy and debridement procedures, might be necessary in severe cases of NS. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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